关键词: 坐骨神经, 损伤, 骨骼肌桥接, 神经移植

Abstract: Objective To evaluate the effects of bridging by skeletal muscle（semi-anastomsois and semi-implantation method）and nerve graft on defect of the peripheral nerves,discuss the use of semi-anastomsois and semi-implantation method in clinic. Methods Fifteen Wistar rats (weight of 200～300 ｇ) were selected to experiment. The sciatic nerves were sutured by semi-anastomsois and semi-implantation with skeletal muscle on left. At the same time, right common peroneael nerves were treated by the nerve graft, the changes of the two sides were measured after three months. Results After three months,the functions of two legs resumed.By macrography and observing under microscope,nerve electrophysiology, histology, there was no significant difference between two groups in the number regenerated fiber crossed sectional area. The effects of semi-anastomsois and semi-implantat ionwith skeletal muscle was as same as nerve graft. Conclusion The method of semi-anastomsois and semi-implantation with skeletal muscle not only operates easily but also saves time and inosculates reliably.It would be a potential method on restoring nerve defect .It has applicable value.

Key words: sciatic nerve, injury, bridging with skeletal muscle, nerve graft