关键词: 直肠肿瘤；临床特征；预后

Abstract:

Abstract:Objective To investigate the clinical characteristics of young rectal carcinomain in order to improve the diagnostic level and therapeutic efficacy at the early stage.Methods Clinical data,including clinical manifestations,misdiagnosis,clinical pathology and prognosis which from 47 cases of young rectal carcinoma were analyzed retrospectively and compared with those from 99 cases of old rectal carcinoma. Results The average course of disease was 6.98 months in young patient group,it was shorter than that in old patient group(9.16 months).The misdiagnosis rate of young group(61.70%) was significantly higher than that in old group(28.28%)(P<0.05).　The average distance between tumor and the anal verge was 6.94 cm in young group and  7.01 cm in old group, there was no difference between them. The occurrence of mucouis adenocarcinoma,low differentiated adenocarcinoma,and signet cell carcinoma in young group (52.18%) was higher than that in old group(30.52%)(P<0.05).Lymph node metastasis was found in 52.17% of young patients,which was much higher than old group(23.16%) ( P<0.05).Both preoperative and postoperative complications in young group were less than those in old group (P＜0.05).The overall 5-year survival rates in young and old groups were similar(45.7% and 56.2%)(P＞ 0.05).Conclusion Compared with the old patients,advanced stage and poorly differentiated carcinoma are more common in young patients with rectal carcinoma.But the 5-year survival rates of the young and old patients are similar.In addition,T stage and lymph node metastasis are the independent prognostic factors. Therefore,early diagnosis and treatment are crucial to improve the survival rate in young patients with rectal carcinoma.

Key words: rectal neoplasms;clinical characteristics;prognosis