支架置入前后颅内动脉瘤血流动力学的数值模拟

J4 ›› 2011, Vol. 37 ›› Issue (5): 894-897.

支架置入前后颅内动脉瘤血流动力学的数值模拟

卢海涛¹|黄清海¹|刘建民¹|陈家亮²|王盛章²

1.第二军医大学上海长海医院神经外科|上海 200433；2. 复旦大学力学与工程科学系,上海　200433

收稿日期:2010-11-22 出版日期:2011-09-28 发布日期:2011-09-28
通讯作者: 刘建民(Tel:021-65492727,E-mail：liu118@vip.163.com) E-mail:liu118@vip.163.com
作者简介:卢海涛(1976-)|男|上海市人|主治医师|医学博士|主要从事脑血管病的基础与临床研究。
基金资助:
上海市自然科学基金资助课题（08ZR1404200）;上海市优秀学科带头人项目资助课题（07XD14026）;上海市科委重点项目基金资助课题（074119506）

Numerical simulation of hemodynamic of intracranial aneurysms before and after stent implantation

LU Hai-tao¹,HUANG Qing-hai¹,LIU Jian-min¹,CHEN Jia-liang²,WANG Sheng-zhang²

1.Department of Neurosurgery,Changhai Hospital, Second Military Medical University,Shanghai 200433,China;2. Department of Mechanics and Engineering Sciences,Fudan University,Shanghai 200433,China

Received:2010-11-22 Online:2011-09-28 Published:2011-09-28

摘要/Abstract

摘要：

目的：探讨支架植入对大脑中动脉(MCA)分叉处动脉瘤的血流动力学影响，以及支架对血流动力学因素特别是壁面切应力(WSS)的影响。方法：结合临床影像，基于计算流体力学(CFD)数值模拟方法，采用ANSYS流体力学软件，对单支架治疗1例MCA分叉处动脉瘤行术前、随访时血流动力学数值模拟分析，比较血液流线和WSS在2种情况下的变化。结果：支架植入后血管形态学发生显著变化，动脉瘤消失，MCA血管分叉夹角由196.4°变小为92.5°。WSS在动脉瘤壁的分布变得更均匀，瘤颈处的高壁面压力区域消失。结论：支架植入明显改变动脉瘤和载瘤动脉的局部血流动力学；CFD数值模拟能直观反映动脉瘤的血流动力学特点
。

关键词: 颅内动脉瘤;血液动力学过程;计算流体力学

Abstract:

Abstract:Objective To explore the effect of stent implantation on the hemodynamic characteristics of middle cerebral artery(MCA) aneurysm and analyze the effect of stent on hemodynamic factors such as wall shear stress.Methods One patient with wide-neck MCA bifurcation aneurysm was analyzed before operation and during follow-up according to clinical images and using fluid dynamics software (ANSYS software) based on computational fluid dynamics(CFD) numerical simulation methods.The blood streamlines and wall shear stress were compared in both conditions.Results There was significant change in morphology of arteries after stent implantation and the aneurysm was gone.The angle of vascular bifurcation became smaller from 196.4° to 92.5°.The aneurysm disappeared completely.The distribution of wall shear stress on the surface of aneurysm turned uniform after stent implantation.The region of high wall stress value near the neck of aneurysm was disappeared directly.Conclusion Stent implantation can change the partial hemodynamics of aneurysm and parent artery.The numerical simulation of CFD can directly reflect the hemodynamic characteristics of aneurysm.

Key words: intracranial aneurysms;hemodynamics process;computational fluid dynamics

中图分类号:

卢海涛|黄清海|刘建民|陈家亮|王盛章. 支架置入前后颅内动脉瘤血流动力学的数值模拟[J]. J4, 2011, 37(5): 894-897.

LU Hai-tao,HUANG Qing-hai,LIU Jian-min,CHEN Jia-liang,WANG Sheng-zhang. Numerical simulation of hemodynamic of intracranial aneurysms before and after stent implantation[J]. J4, 2011, 37(5): 894-897.