关键词: 嗜铬细胞瘤；腹腔镜；对比研究

Abstract:

Objective To investigate the clinical efficacy of retroperitoneal laparoscopic surgery of adrenal pheochromocytoma by comparing the differences between open and retroperitoneal laparoscopic surgery of adrenal pheochromocytoma.Methods Based on patients’ requirements and surgeon’s experience,48 patients with  unilateral adrenal pheochromocytoma  were divided into  retroperitoneal laparoscopic group (n=23) and  open surgery group (n=25).The clinical efficacies in two groups were compared and  the differences between them in operation time,blood loss,intraoperative blood pressure control,postoperative hospitalization time and the incidence of postoperative complications were investigated.Results The operation in two  groups was successful.In retroperitoneal laparoscopic group and open surgery group,the  operation time were (60±25) min and (100±40) min,the blood loss were (42±16) mL and (156±45) mL,the blood pressure in operation  were(160±10) mmHg and (165±55) mmHg,the postoperative hospitalization time  were (5.2±1.2)d and (7.4±1.6) d.there were significant differences between two groups（all P<0.01）.There were no major postoperative complications.All the 48 cases were pathologically diagnosed as pheochromocytoma.All patients were followed up for 6-48 months,their clinical  symptoms disappeared.No tumor recurrences developed.Conclusion Retroperitoneal laparoscopic surgery is superior to open surgery in treating adrenal pheochromocytoma patients,which has less bleeding,less trauma and quicker recovery.It is therefore a safe and effective method in treating pheochromocytoma.

Key words: pheochromocytoma;laparoscope;comparative study