轴外型桥小脑角区髓母细胞瘤2例报告及文献复习

doi:10.13481/j.1671-587x.20190340

吉林大学学报(医学版) ›› 2019, Vol. 45 ›› Issue (03): 701-704.doi: 10.13481/j.1671-587x.20190340

• 临床医学 • 上一篇

轴外型桥小脑角区髓母细胞瘤2例报告及文献复习

常盼盼, 韩帅, 别黎, 李毅平

吉林大学第一医院神经外科, 吉林长春 130021

收稿日期:2018-08-01 发布日期:2019-06-05
通讯作者: 李毅平,教授,主任医师,硕士研究生导师(Tel:0431-88782331,E-mail:lyp0518@163.com) E-mail:lyp0518@163.com
作者简介:常盼盼(1986-),男,山西省临汾市人,在读医学硕士,主要从事胶质瘤基础和临床方面的研究。
基金资助:
国家自然科学基金资助课题（81201980）

Extra-axial medulloblastoma in cerebellopontine angle: A report of two cases and literature review

CHANG Panpan, HAN Shuai, BIE Li, LI Yiping

Department of Neurosurgery, First Hospital, Jilin University, Changchun 130021, China

Received:2018-08-01 Published:2019-06-05

摘要/Abstract

摘要： 目的：探讨轴外型桥小脑角（CPA）区髓母细胞瘤（MB）的临床特点，分析其影像学特征和临床预后，为其临床诊断和治疗提供参考。方法：收集2例诊断为轴外型CPA区MB患者的临床资料；结合相关文献，分析该病的临床特点、诊断和治疗方法。结果：2例患者因头痛伴听力下降入院，头部核磁共振（MRI）平扫及增强提示CPA占位性病变。2例患者均行CPA区肿瘤切除术。2例患者手术顺利，术中可见肿瘤位于轴外，术后病理证实为MB，随访15个月未见肿瘤复发和转移。结论：对于轴外型CPA占位性病变，术前应考虑MB的可能性。积极的手术治疗有助于改善预后并延长患者的生存期。

关键词: 轴外, 桥小脑角, 髓母细胞瘤, 预后

Abstract: Objective:To investigate the clinical features of extra-axial medulloblastoma(MB) in the cerebellopontine angle(CPA) area and analyze the imaging features and clinical prognosis, and to provide the reference for its clinical diagnosis and treatment. Methods:The clinical data of two patients diagnosed as extra-axial MB in CPA area were collected;the literature review was performed,and the clinical characteristics,diagnostic and treatment methods were analyzed. Results:Two patients were admitted to the hospital due to headache accompanied by hearing loss.The magnetic resonance imaging (MRI) results indicated a mass in the CPA area.All the two patients were treated with the cerebellopontine angle tumor resection. The operation of the two patients was successful, and the tumor located outside the axis seen in the operation, which was confirmed as MB by postoperative pathology. No recurrence or metastasis of tumor was found 15 months after follow-up. Conclusion:The possibility of MB should be considered before operation for the occupying lesions in the extra-axial CPA area.The active operation can improve the prognosis and prolong the survival of the patients.

Key words: extra-axial, cerebellopontine angle, medulloblastoma, prognosis

中图分类号:

R739.41

常盼盼, 韩帅, 别黎, 李毅平. 轴外型桥小脑角区髓母细胞瘤2例报告及文献复习[J]. 吉林大学学报(医学版), 2019, 45(03): 701-704.

CHANG Panpan, HAN Shuai, BIE Li, LI Yiping. Extra-axial medulloblastoma in cerebellopontine angle: A report of two cases and literature review[J]. Journal of Jilin University(Medicine Edition), 2019, 45(03): 701-704.

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轴外型桥小脑角区髓母细胞瘤2例报告及文献复习

Extra-axial medulloblastoma in cerebellopontine angle: A report of two cases and literature review

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