关键词: 儿童, 白癜风, 危险因素

Abstract:

Objective: To explore the clinical characteristics and the risk factors of vitiligo in children,and to provide basis for the personalized invention treatment in clinic.Methods: A total of 1 040 patients with vitiligo treated in our hospital were divided into children group(n=271,age≤12 years) and adult group(n=769,age>18 years); physical examination and a standardized questionnaire were used to collect the data and the clinical characteristics and the risk factors were analyzed.Results: In 271 children patients with vitiligo, the ratio of male to female was about 1:1,there was no significant difference compared with adult group(P>0.05). The high season of vitiligo in children and adult groups were spring and summer. The ratios of segmental vitiligo and focal vitiligo in children group were siginificantly higher than those in adult group(P<0.05); the incidence of sporadic type, generalized type and acral type in children group was lower than that in adult group(P<0.05).The most common precipitating factors of vitiligo in children group were dermatosis and trauma(14.76%,13.28%), but the psychological factors were the most common precipitating factors in adult group(29.39%).The incidence of halo nevi in children group was higher than that in adult group(P<0.05).There was no significant difference in the percentages of the patients with positive family history of vitiligo between children and adult groups(P>0.05).Conclusion: There are some differences in clinical characteristics of vitiligo between the children and the adults.Dermatosis,trauma and halo nevi are the major risk factors of vitiligo in the children.

Key words: vitiligo, children, risk factors