关键词: 治疗, 支架, C反应蛋白

Abstract: Objective To investigate the effects of rapamycin eluting stent　（Cypher^TM） and metal bare stent on the prognosis and C-reactive protein (CRP)　in elderly patients with acute myocardial infarction (AMI). Methods The immediate angiographic and clinic follow-up outcomes of 45 elderly patients with AMI reciving Cypher^TM and bare stent were retrospectively analyzed. CRP levels in Cypher^TM and bare stent groups were determined before implantation, 6 h, 1　d, 7 d and 30 d after implantation . Clinical follow-up and major coronary events analysis were developed after operation. Results 27 rapamycin eluting stents were implanted in patients of Cypher^TM group and 26 bare stents were implanted in patients of bare stent group.The Cypher^TM stents were successfully implanted with 100%.　In patients of Cypher^TM group,no serious complications were found in the term of operation and in hospital.There was no restenosis, revascularization and events. In patients of bare stent group,except for 1 patients with sudden death,angina pectoris occurred in 2 patients, repeat angiography showed that there were new lesions in other coronary arteries of these patients. Restenosis attacked in 2 patients. The concentrations of CRP in Cypher^TM and bare stent groups 6 h and 7 d after operation were much higher than that of pre-operation (P<0.05). Conclusion Repamycin eluting stent（Cypher^TM）shows a safety profile and potential efficacy in the treatment of elderly patients with AMI.

Key words: therapy, stent, C reactive protein