关键词: 治疗, 聚焦超声, 外阴上皮内非瘤样病变

Abstract: Objective To investigate the clinical curative effects of focused ultrasound treatment for nonneoplastic epithelial disorders of vulva. Methods Seventy-five patients (aging 12-69, mean 36.81 years) with nonneoplastic epithelial disorders of vulva were confirmed by pathology, including thirty-six patients with squamous hyperplasia, twenty-eight patients with lichen sclerosus accompanied and eleven patients with lichen sclerosus acco mpanied with squamous hyperlasia. All of them were randomly assigned to two groups. 45 cases in the ultrasound group were treated with Seapostar (model: CZF) ultrasound treatment instrument. The power of 4.0　W was used for 20-40 min in each session. The other 30 patients were received medical routine treatment. A duration of 90 d was treatment course. Results All patients in ultrasound group recovered at different degrees,among them 12 cases (26.7%) were cured,28 cases (62.2%) were obviously improved，5 cases (11.1%)were improved. The effective rate was 100%. The pa thological changes indicated that the squamous epithelium of vulva has recovered normal stratification and thickness. In the control group, 1 case (3.3%) was cured,5 cases (63.3%) were obviously improved and 19 cases (16.7%) were improved. But 21 cases (70.0%) were found relapsed pruritus of vulva 1-2 months after treatment. Conclusion The focused ultrasound treatment is a new effective and safe method for nonneoplastic epithelial disorders of vulva.

Key words: therapy, focused ultrasound, nonneoplastic epithelial disorders of vulva