不同金属烤瓷冠修复患者龈沟液中IL-6浓度测定及Ni 离子对牙龈的影响

J4 ›› 2010, Vol. 36 ›› Issue (6): 1111-1113.

不同金属烤瓷冠修复患者龈沟液中IL-6浓度测定及Ni 离子对牙龈的影响

李美华¹, 李秋实², 张天夫¹

1.吉林大学中日联谊医院口腔科|吉林长春130033 ；2.吉林大学口腔医院VIP诊室|吉林长春130021

收稿日期:2010-09-05 出版日期:2010-11-28 发布日期:2010-11-28
通讯作者: 张天夫（Tel：0431-84995573，E-mail:zhangtianfu1963@sina.com） E-mail:zhangtianfu1963@sina.com
作者简介:李美华（1963-）,女| 黑龙江省鹤岗市人| 教授| 医学博士| 主要从事口腔修复研究。
基金资助:
吉林省科技厅白求恩医学专项基金资助课题（200705312）

Detection of IL-6 level in GCF and influence of Ni＋on |gingiva in patients with different porcelain-fused-to-metal crowns

LI Mei-Hua¹, LI Qiu-Shi², ZHANG Tian-Fu¹

1.Department of Stomatology,China-Japan Union Hospital,Jilin University,Changchun 130033,China;2.Department of VIP,Stomatology Hospital,Jilin University,Changchun 130021,China

Received:2010-09-05 Online:2010-11-28 Published:2010-11-28

摘要/Abstract

摘要：

目的：通过龈沟液(GCF)中白细胞介素6(IL-6)浓度的测定,评价不同金属烤瓷冠(PFM)对牙龈组织的刺激性。方法：欲行PFM修复的牙列缺失患者60例分别采用镍铬合金、镍铬合金镀金及金合金进行修复，每组20例，以修复对侧同名牙或对牙合同名牙为各自对照组。PFM修复6个月后，采集并定量GCF，采用酶联免疫吸附法测定GCF中IL-6的浓度。结果：金合金组GCF分泌量与对照组比较差异无显著性（P>0.05）；镍铬合金镀金组及镍铬合金组GCF分泌量显著高于金合金组及对照组（P<0.05），而镍铬合金镀金组与镍铬合金组比较差异无显著性（P>0.05）。金合金组、镍铬合金镀金组GCF中IL-6浓度与对照组比较差异无显著性（P>0.05），镍铬合金组GCF中IL-6浓度显著高于对照组（P<0.05）；金合金、镍铬合金镀金组GCF中IL-6浓度显著低于镍铬合金组（P<0.05），而金合金与镍铬合金镀金组比较差异无显著性（P>0.05）。结论：含镍金属对牙龈刺激最大，金合金烤瓷冠对牙龈组织刺激性最小，GCF中IL-6的浓度可以作为监测PFM修复效果的理论指标。

关键词: 金属烤瓷冠；牙龈组织；龈沟液；白细胞介素6

Abstract:

Abstract:Objective To evaluate the effect of porcelain-fused-to-metal(PFM) crowns with different metal alloy base on the gingiva by detecting the IL-6 level in gingival crevicular fluid(GCF). Methods Ni-Cr alloy,gilt Ni-Cr alloy,gold alloy PFM were employed to total of 60 clinical patients. 6 months later,GCF from the patients was collected and quantified,and the IL-6 level was detected by ELISA kit. Results There was no significant difference of the GCF between gold alloy group and control group(P>0.05);the GCF in Ni-Cr alloy group was much higher than those in gold alloy group and control group (P<0.05),and there was no significant difference between Ni-Cr alloy group and gilt Ni-Cr alloy group (P>0.05). The IL-6 levels in GCF in Ni-Cr alloy group was much higher than that in control group (P<0.05), there were no significant differences between gilt Ni-Cr alloy group,gold allog group and control group(P>0.05).There was no significant difference of IL-6 level between gilt Ni-Cr alloy group and gold alloy group (P>0.05),the IL-6 levels in gilt Ni-Cr alloy group and gold alloy group were much lower than that in Ni-Cr alloy group(P<0.05). Conclusion Ni alloy has the most serious stimulation,and gold alloy has the least effect on the gingiva.The IL-6 level in GCF could be a theoretical index to monitor clinical effect of PFM.

Key words: porcelain-fused-to-metal;gingival tissue;gingival crevicular fluid;interleukin-6

中图分类号:

R783

李美华, 李秋实, 张天夫. 不同金属烤瓷冠修复患者龈沟液中IL-6浓度测定及Ni 离子对牙龈的影响[J]. J4, 2010, 36(6): 1111-1113.

LI Mei-Hua, LI Qiu-Shi, ZHANG Tian-Fu. Detection of IL-6 level in GCF and influence of Ni＋on |gingiva in patients with different porcelain-fused-to-metal crowns[J]. J4, 2010, 36(6): 1111-1113.

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