Abstract:

Objective To compare the clinical efficacies of transurethral plasmakinetic enucleation of prostate （PKEP） and transurethral plasmakinetic resection of prostate （PKRP） in the treatment of benign prostatic hyperplasia （BPH）， and provide the evidence for the treatment options for BPH. Methods The clincal data of 60 patients with lower urinary tract symptoms （LUTS） and initial diagnosis as BPH were collected. With the patients’ informed consent， they were divided into PKEP group （treated with PKEP） and PKRP group（treated with PKRP）， and there were 30 cases in each group. The age， body weight， body mass index （BMI）， total prostate-specific antigen （tPSA） level， hematocrit （HCT）， hemoglobin （Hb） level，preoperative and postoperative sodium ion level， prostate volume，degree of midlobe median lobe protrusion， occurrence of complications （hypertension， diabetes， and respiratory diseases）， percentage of oral 5α-reductase inhibitor using， operation time，amount of intraoperative blood， resected tissue volume， resection rate，resection efficiency，total hospital stay after operation，indwelling catheterization time， bladder irrigation duration， sodium ion level，Quality Of Life （QOL） score， and International Prostate Symptom Score （IPSS） before and after operation of the patients in two groups were observed and compared.The incidences of adverse reactions of the patients in two groups after operation were also compared. Results There were no significant differences in age， body weight， BMI，tPSA level， preoperative HCT， preoperative Hb level，sodium ion level before operation， prostate volume， and degree of midlobe protrusion of the patients between two groups （P>0.05）. There were no statistically significant differences in the occurrences of complications （hypertension， diabetes， and respiratory diseases） and the percentage of oral 5α-reductase inhibitor using of the patients between two groups （P>0.05）； the amount of blood during operation， resected tissue volume， resection rate， and resection efficiency of the patients in PKRP group were higher than those in PKEP group （P<0.05）； there were no significant differences in the total hospital stay，indwelling catheterization time， and bladder irrigation duration after operation of the patients between two groups （P>0.05）； there were no significant differences in the sodium ion levels， QOL scores， and IPSS of the patients between two groups before and after operation（P>0.05）； there were significant differences in the QOL scores and IPSS of the patients in each group before and after operation （P<0.05）.There was one case of urinary incontinence in PKEP group and two cases of urinary incontinence in PKRP group， without other operation-related complications. Conclusion Both two methods have similar efficacy and safety， and can achieve the satisfactory surgical outcomes.The patients undergoing PKEP have less amount of blood during operation， higher resected tissue volume，the higher resection efficiency， and higher resection rate， which is a better way to treat BPH.

Key words: Benign prostatic hyperplasia, Transurethral plasmakinetic enucleation of prostate, Transurethral plasmakinetic resection of prostate, Resection rate, Resection efficiency