Journal of Jilin University(Medicine Edition) ›› 2024, Vol. 50 ›› Issue (3): 872-880.doi: 10.13481/j.1671-587X.20240335

• Review • Previous Articles    

Research pregress in pain matrix of postherpetic neuralgia

Qiuping LIU1,2,Tao LIU1,2,Xuezhu ZHANG1,2()   

  1. 1.Insitute of Acupun Reaserch,First Affiliated Hospital,Tianjin Uniersity of Tradtional Chinese Medicine,Tianjin 300193,China
    2.National Clinical Research Center for Acupuncture and Moxibustion,Tianjing 300193,China
  • Received:2022-11-18 Online:2024-05-28 Published:2024-07-01
  • Contact: Xuezhu ZHANG E-mail:zhangxuezhu1999@126.com

Abstract:

Postherpetic neuralgia (PHN) is a typical chronic neuropathic pain syndrome. Both peripheral and central nervous system mechanisms are believed to be involved in PHN, but the central nervous system-related brain network structure and function are not yet fully elucidated, limiting the study on the clinical analgesic drugs and other intervention strategies. In recent years, the research on pain matrix-related brain networks has helped to reveal the central nervous system regulation mechanism of pain, but there are few reports on the PHN pain matrix. This review summarizes the recent studies on the PHN pain matrix, retrospectively analyzes the functional and structural changes in specific pain-related brain regions, in order to provide the new insights for exploring the effective targeted analgesic treatments.

Key words: Postherpetic neuralgia, Pain matrix, Brain region, Certral nervous system, Pain syndrome

CLC Number: 

  • R752.12