Abstract:

Objective To investigate the distribution of common pathogens in different departments and drug resistance of these pathogens in the patients with urinary tract infections in our hospital, and to provide reference basis for selecting reasonable, timely and personal treatment plan with effective antibiotic agents for the patients in different clinical departments. Methods 252 urine samples with positive culture from the hospitalized patients were collected and the sensitivity Results and bacterial resistance rates were obtained.The distribution of 270 strains isolated from 252 samples and the susceptibility Results were analyzed and the drug resistance of bacteria in different departments was compared. Results In 270 strains, the number of gram-negative bacteria was 202 (74.81%), Escherichia coli was the most common pathogen (121, 44.81%), followed by Klebsiella pneumoniae (24, 8.89%), Pseudomonas aeruginosa (10, 3.70%), Klebsiella oxytoca (9, 3.33%);In gram-positive bacteria, feces Enterococcus was the most common pathogen (20, 7.41%), followed by Viridans (12, 4.44%), Enterococcus faecalis (10, 3.70%);ESBLs-producing pathogens were 28 strains which accounted for 13.86% of all bacteria.The number of meropenem-resistant bacteria was 8 strains.All feces Enterococci were sensitive to linezolid and teicoplanin, but of which the resistance rate was 5.0% for vancomycin.The pathogens were different in different departments, such as the number of feces Enterococcus in ICU was the most, followed by Escherichia coli;in VIP ward, the infection rates of Enterococci and Escherichia coli in the patients were the same;in other major departments the Escherichia coli had the highest proportion of bacteria. Conclusion Bacilus is the main pathogenic bacterium in the patients with urinary tract infections, but the coccus should be paid attention.The pathogenic bacteria have resistance to many drugs, and the main pathogenic bacteria vary in different departments, so the personal treatment plan for different patients should be made.

Key words: urinary tract infections, pathogenic bacteria, antibiotics, drug resistance rate