Abstract: Objective:To observe the curative effect of 25-gauge mini-invasive system in cataract surgery after vitrectomy,and to provide a safe operation method for the patients with cataract induced by vitrectomy. Methods: A total of 29 patients (30 eyes) with cataract after vitrectomy were selected. Phacoemulsification and implantation of artificial lens with 25-gauge mini-invasive irrigation system were performed in the patients.The best corrected visual acuity(BCVA),intraocular pressure(IOP),corneal endothelial cell loss rate,intraoperative and postoperative complications of the patients were observed. Results: All the patients received the operation successfully. One month after operation,BCVA ≥ 0.5 were found in 5 eyes,0.3-0. 5 in 8 eyes,0.1-0.3 in 9 eyes,Fc-0.1 in 8 eyes; the BCVA 1 month after operation had significant differences compared with before operation(P<0.05).The mean IOP before operation and 1 d,7 d,1 month,3 months after operation were (17.13±2.84),(17.20±4.16),(17.43±3.41),(17.36±2.51),and(16.73±2.33)mmHg;the IOP of the patients at 1 d after operation had significant difference compared with before operation(P<0.05).No statistically significant differences of IOP were found between other groups(P>0.05).The number of corneal endothelial cells before operation was(2 467±280)mm^-2 and the number after operation was (2 033±209)mm^-2;the loss rate of corneal endothelial cells was 17.59%.There were no sever complications such as retinal redetachment,detachment of choroid,capsular rupture or suprachoroidal hemorrahage. Conclusion: Phacoemulsification for cataract after vitrectomy with 25G mini-invasive system way can maintain the IOP,reduce the complications and enhance the security in cataract surgery.

Key words: cataract, vitrectomy, 25G irrigation, phacoemulsification