300例特发性间质性肺炎患者生活质量现状及影响因素分析

doi:10.13481/j.1671-587x.20190525

Abstract

Abstract: Objective:To explore the influencing factors related to the quality of life of the patients with idiopathic interstitial pneumonia (ⅡP), and to provide the theoretical basis for improving the quality of life, preventing other complications,and improving the prognosis of the patients with ⅡP. Methods:St George's Respiratory Questionnaire (SGRQ) was used to evaluate the quality of life of 300 hospitalization patients with ⅡP who met the inclusion criteria in the study. The differences of quality of life among different groups of people were compared. A general linear regression model was used to screen the independent influencing factors that may affect the scores of quality life of all dimensions. Results:Drinking, forced vital capacity (FVC) and 6 min walk test (6MWT) were the independent influencing factors of the symptom score of the ⅡP patients (P<0.05); nation, family per capita monthly income, carbon monoxide diffusion capacity (DLCO), and 6MWT were the independent influencing factors of activity limit score of the ⅡP patients (P<0.05); nation, family per capita monthly income, FVC, and 6MWT were the independent influencing factors of life impact score of the ⅡP patients (P<0.05); nation, family per capita monthly income, FVC, and 6MWT were the independent influencing factors of the scores of quality of life of the ⅡP patients (P<0.05). Conclusion:The activity limit of ⅡP patients is more obvious. Drinking, nation and family per capita monthly income, FVC, 6MWT and DLOC are the factors affecting the quality of life of the ⅡP patients in different dimensions.

Key words: idiopathic interstitial pneumonia, St George’s respiratory questionnaire, quality of life, lung function, influencing factors

CLC Number:

R563.13

WANG Yanjun, QU Danhua, GUO Xin, YAO Yan, CHENG Yuanjuan. Analysis on present situation of quality of life and its influencing factors of 300 cases of patients with idiopathic interstitial pneumonia[J].Journal of Jilin University(Medicine Edition), 2019, 45(05): 1119-1127.

References

[1] COULTAS B, ZUMWALT E, BLACK C, et al. The epidemiology of interstitial lung diseases[J]. Am J Respir Crit Care Med, 1994, 150(4):967-972.
[2] 宗晓福, 汪凤凤, 苗伟伟, 等. 特发性急性嗜酸粒细胞性肺炎一例临床特征分析[J]. 国际呼吸杂志, 2012, 32(19):1454-1456.
[3] COTTIN V, HIRANI N A, HOTCHKIN D L, et al. Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases[J]. Eur Respir Rev, 2018, 27(150):180076.
[4] ATZENI F, GERARDI M C, BARILARO G, et al. Interstitial lung disease in systemic autoimmune rheumatic diseases:a comprehensive review[J]. Expert Rev Clin Immunol, 2018, 14(1):69-82.
[5] BERRY C E, DRUMMOND M B, HAN M K, et al. Relationship between lung function impairment and health-related quality of life in COPD and interstitial lung disease[J]. Chest, 2012, 142(3):704-711.
[6] VAN DER MOLEN T, WILLEMSE B W, SCHOKKER S, et al. Development, validity and responsiveness of the Clinical COPD Questionnaire[J]. Health Qual Life Outcomes, 2003, 1:13.
[7] SUZUKI A, KONDOH Y, SWIGRIS J J, et al. Performance of the St George's Respiratory Questionnaire in patients with connective tissue disease-associated interstitial lung disease[J]. Respirology, 2018. https://doi.org/10.1111/resp.13293.
[8] HOLLAND A E, HILL C J, GLASPOLE I,et al. Predictors of benefit following pulmonary rehabilitation for interstitial lung disease[J]. Respir Med, 2012, 106(3):429-435.
[9] 王静宜. N-乙酰半胱氨酸对慢性饮酒大鼠肺纤维化的干预作用[D]. 天津:天津医科大学, 2011.
[10] PEREZ-BOGERD S, WUYTS W, BARBIER V, et al. Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases:a randomised controlled trial[J]. Respir Res, 2018, 19(1):182.
[11] JENSEN D, SCHAEFFER M R, GUENETTE J A. Pathophysiological mechanisms of exertional breathlessness in chronic obstructive pulmonary disease and interstitial lung disease[J]. Curr Opin Support Palliat Care, 2018, 12(3):237-245.
[12] 徐鸥, 郝青林, 李锐洁,等. 圣乔治呼吸问卷对慢性阻塞性肺疾病患者生活质量差异的调查[J]. 昆明医学院学报, 2008, 29(3):71-75,87.
[13] 陈浩, 王莹. 圣乔治呼吸问卷评估慢性阻塞性肺疾病患者生活质量的价值[J]. 安徽医学, 2014,35(8):1052-1054.
[14] 刘义德. 慢性酒精中毒与肺疾病[J]. 中华全科医学, 2012,10(1):100, 165.
[15] 陆影, 徐静, 薛素梅. 新疆不同民族慢性阻塞性肺疾病患者自护能力水平及影响因素分析[J]. 新疆医科大学学报, 2017, 40(6):848-851.
[16] 程恒金, 周慧洁, 李恩慈,等. 护理干预对慢性阻塞性肺疾病稳定期患者自我管理能力的影响研究[J]. 中国慢性病预防与控制, 2016, 24(2):156-160.
[17] 陈旭, 杨晓芸, 刘淑敏, 等. 老年慢性阻塞性肺疾病患者生活质量调查及干预对策[J]. 中国全科医学, 2017,20(27):3431-3436.
[18] CHAN E D, IRVIN C G. The detection of collapsible airways contributing to airflow limitation[J]. Chest, 1995, 107(3):856-859.
[19] 郑宏兴, 傅科锋, 傅婷霞,等. 肺康复锻炼对慢性阻塞性肺疾病患者活动耐力和生活质量的影响[J]. 中国慢性病预防与控制, 2017, 25(3):210-213.
[20] 申永春,文富强.2017年慢性阻塞性肺疾病全球创议更新解读[J].中国实用内科杂志,2017,37(2):132-135.
[21] 李小萌,徐家欢,李文扬,等.慢性阻塞性肺疾病早期筛查工具的研究现状[J].中国实用内科杂志,2019,39(2):179-184.
[22] 潘金兵, 王思勤, 赵桂华,等. 特发性间质性肺炎肺功能的分析[J]. 实用诊断与治疗杂志, 2006, 20(3):171-172.
[23] 刘佳育. ANCA相关性血管炎肺部表现30例临床分析[D]. 长春:吉林大学, 2012.

Analysis on present situation of quality of life and its influencing factors of 300 cases of patients with idiopathic interstitial pneumonia

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