Abstract:

Abstract:Objective To explore the most appropriate treatment method for  the  patients with intracranial metastatic tumor，and to provide basis for improving the life quality of the patients and prolonging the living time．Methods 186 cases of intraeranial metastatic tumor in our department form 2000 to 2010 were selected and divided into five groups according to the condition and image data: group Ⅰ (operation + radiotherapy + chemotherapy group) with 81 cases, group Ⅱ (radiotherapy + chemotherapy group) with 66 cases,group Ⅲ (chemotherapy group) with 14 cases, group Ⅳ(radiotherapy group) with 14 cases, Ⅴ group (supportive therapy group) with 11 cases.The nerve compression symptoms and treatment effectiveness of intracranial hypertension and the average survival period of the patients were compared between various groups. The statistics analysis was carried for the patients who were followed up.Results There were significantly differences of nerve compression symptoms and treatment effectiveness of intracranial hypertension and the average survival period between group Ⅰ and group Ⅱ,group Ⅲ,group Ⅴ P<0.05);but there were no significantly differences between group Ⅰ and group Ⅳ(P>0.05).Conclusion Individualized treatment should be used in the patients with intracranial metastatic tumor；operation combined with adiotherapy and chemotherapy is the first choice in the patients with good neurological condition, ollowed by radiotherapy.

Key words: intracranial metastatic tumors, individualized treatment, intracranial hypertension, nerve compression symptoms