J4 ›› 2009, Vol. 35 ›› Issue (5): 936-939.

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Evaluation of clinical effect of ZeGuiLongShuang capsules combined with naftopidil on benign prostatic heperplasia

 LI Zhi1, WANG Yao2, WANG Wei-Hua2, ZHANG Yong-Ge3   

  1. (1.Department of Pharmacy Service,Second Affiliated Hospital,General Hospital of PLA,Beijing 100850,China;2.Department of Urinary Surgery,China-Japan Union Hospital,Jilin Uiversity,Changchun 130021,China;3.School of Basic Medical Sciences of Combination of Chinese Traditional and Western Medicine,Changchun University of Traditional Chinese Medicine,Changchun 130117,China)
  • Received:2009-02-27 Online:2009-09-28 Published:2009-10-13

Abstract:

Abstract:Objective
To study the curative effect of ZeGuiLongShuang capsules combined with naftopidil on benign prostatic hyperplasia(BPH). Methods 140 cases with BPH were randomly divided into treatment group and control group.The patients in treatment group were given ZeGuiLongShuang capsules(once 2 tablets,3 times a day) combined with naftopidil(once 25 mg,once a day before sleeping).The patients in  control group were given only naftopidil(once 25 mg,once a day before sleeping).Internatianal-prognosic-scoring-system(IPSS),uroflowmetry-max(Qmax),Quality-of-life(QOL),residual urine and weight of prostate before and after treatment were detected.Results IPSS,Qmax,QOL and residual urine changed in two  groups.IPSS,Qmax,QOL and residual urine in treatment group were more significant than those in control group(P<0.05).There was little change of weight of prostate.Conclusion There is no remarkable side effect of ZeGuiLongShuang capsules combined with naftopidil.ZeGuiLongShuang capsules combined with naftopidil is highly effective for BPH by decreasing rational symptom and objective index and improving the life quality of patients with BPH.

Key words: prostatic heperplasia;chinese patent drugs , medicine;ZeGuiLongShuang capsules;Naftopidil
                    

CLC Number: 

  • R697.32