Abstract:

Abstract:Objective To analyze the results of ⁹⁹Tcm-MIBI imaging and parathyroid hormone (PTH) measurement of the patients withsuspected primary hyperparathyroidism (PHPT) and to evaluate the diagnostic value of ⁹⁹Tcm-MIBI imaging combined with PTH measurement in PHPT.
Methods The results of ⁹⁹Tcm-MIBI imaging and serum PTH measurement in 43 patients with suspected PHPT were retrospectively analyzed.The postoperative pathology was used as the golden standard for PHPT.The sensitivities，specificities，positive predictive values， negative predictive values，accuracies，negative likelihood and positive likelihood of ⁹⁹Tcm-MIBI imaging,PTH measurement,99Tcm-MIBI imaging combined with serum PTH
 measurement were compared and evaluated.Results The sensitivities，specificities，positive predictive values， negative predictive values，negative likelihood,positive likelihood and accuracies of ⁹⁹Tcm-MIBI imaging,PTH measurement and  ⁹⁹Tcm-MIBI imaging combined with serum PTH measurement were 93.75％,84.38％,100%; 45.50％,54.55％,36.36%; 83.33％,84.38％,88.89%; 71.4％,54.55％,100%; 1.72,1.85,1.57; 0.14,0.29,0;81.40％,76.74％,83.72%.
Conclusion 99Tcm-MIBI imaging combined with serum PTH measurement can increase the diagnostic accuracy and decrease the rate of missed diagnosis.
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Key words: hyperparathyroidism, 99Tcm-MIBI imaging, parathyroid hormone