A型肉毒毒素局部注射对脑卒中患者下肢肌痉挛和步行能力的改善作用

doi:10.13481/j.1671-587x.20160332

Abstract

Abstract:

Objective: To observe the effect of botulinum toxin A injection treatment on the spasticity of triceps surae and walking ability of the patient with stroke,and to discuss the relationship between the muscle tension changes and motor function of lower limb and the feasibility of its application in the community rehabilitation. Methods: Thirty stroke patients with triceps surae spasticity were divided into treatment group(n=15) and control group(n=15) according to the patient's will.In treatment group,the botulinum toxin A were injected into the triceps surae of patients before routine physical therapy,while the patients in control group only received routine physical therapy,including muscular stretching,treatment of muscle strength,balance function and walking ability.The modified Ashworth scale (MAS),Fugl-Meyer Assessment (FMA) and 10-meter walk test (10MWT) time were used to detect the ability of lower limb.All the test was performed before,after,and 3 months after the treatment. Results: The MAS scores of the patients in treatment group after treatment and 3 months after treatment were lower than that before treatment (P<0.05);there was no significant difference of MAS scores of the patients in control group after treatment(P>0.05),and the MAS score of patients 3 months after treatment was lower than that before treatment(P<0.05).The FMA score and 10MWT time of the patients in two groups after treatment and 3 months after treatment were higher than those before treatment(P<0.05).Compared with control group,the MAS scores and 10MWT time of the patients in treatment group after treatment and 3 months after treatment were decreased and the FMA scores were increased(P<0.05). Conclusion: The botulinum toxin A treatment combined with routine physical therapy may improve the spasticity of triceps surae,gait,and walking ability in a better way,which can be applied in the community rehabilitation.

Key words: stroke, spasticity, botulinum toxin A, walking ability, community rehabilitation

CLC Number:

R743.3

CHEN Xiaowei, CHENG Shihuan, LI He, ZHANG Chunsheng, YI Aizhi, LI Zhenlan. Improvement effect of botulinum toxin A injection treatment on spasticity of triceps surae and walking ability of patients with stroke[J].Journal of Jilin University Medicine Edition, 2016, 42(03): 582-586.

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Improvement effect of botulinum toxin A injection treatment on spasticity of triceps surae and walking ability of patients with stroke

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