Journal of Jilin University Medicine Edition ›› 2016, Vol. 42 ›› Issue (06): 1151-1156.doi: 10.13481/j.1671-587x.20160620

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Evalution on curative effect of Compound Zikui Yuanyang Capsule in treatment of patients with benign prostatic hyperplasia

LI Jiayin1, WANG Shichao2, QUAN Chengshi1, LI Lisha1, LIU Minru3, LI Yulin1   

  1. 1. Department of Pathology, School of Basic Medical Sciences, Jilin University, Key Laboratory of Pathobiology, Ministry of Education, Changchun 130021, China;
    2. Department of Obstetrics and Gynecology, China-Japan Union Hospital, Changchun 130033, China;
    3. Department of Traditional Chinese Medicine Gynecology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • Received:2016-09-14 Online:2016-11-28 Published:2016-12-02

Abstract:

Objective: To discuss the therapeutic effect of Compound Zikui Yuanyang Capsule in the treatment of the patients with benign prostatic hyperplasia (BPH), and to illuminate the clinical effect of Compound Zikui Yuanyang Capsule in the treatment of the BPH patients with obvious kindney deficency syndrome.Methods: A total of 66 patients were divided into experimental group (given Zikui Yuanyang Capsule) and control group (given placebo). The International Prostate Symptom Score (I-PSS), Qmax,Quality of Life Score (QOL), International Index of Erectile Function(ⅡEF),and testosterone level of the patients in two groups were detected before and after treatment.Results: In Chinese medicine symptoms, the percentages of patients with clinical control,marked effectivness,and effectiveness in experimental group and control group were 10%, 13%, 57% and 0%, 6.25%, 16.00%, respectively, and the total effective rates were 86.00% and 22.25%, respectively; the total effective rate of the patients in experimental group was superior to that in control group (P<0.05). In the main symptoms, the number of the patients with frequent urination disorder, more night urination number, and dysuria in experimental group was less than that in control group (P<0.05). Conclusion: Compound Zikui Yuanyang Capsule has better clinical efficacy and safety in the treatment of the BPH patients with kidney deficiency symptoms.

Key words: Compound Zikui Yuanyang Capsule, kidney deficiency symptom, benign prostatic hyperplasia

CLC Number: 

  • R697.3