Abstract:

Abstract:Objective
 To exploit the medicinal values of Scorzonera ruprechtiana Lipsch.et Krasch.through investigating its chemical constituents. Methods  The herbs of Scorzonera ruprechtiana were extracted with 70% ethanol,the extractives were purified with  macroporous resin and isolated with silica gel,and ODS column chromatography.NMR,UV,IR spectrometers were used to obtain spectroscopic data.
Results  According to the single spot in TLC,three flavonoid glycoside compounds and one sesquiterpenoid glycoside compound were isolated from the herbs of Scorzonera ruprechtiana,and their structures were identifited through physico-chemical constants and spectroscopic analysis.They were 5,7,3′,4′-tetrahydroxy-flavone 8-C-β-D-glucopyranoside (Ⅰ); 5,7,3′,4′-tetrahydroxy- flavone 6-C-β-D- glucopyranoside (Ⅱ); 5,7,4′-trihydroxy- flavone 6-C-β-D- xylofuranosyl-(1→2)-β-D- glucopyranoside (Ⅲ);3-O-β-D- glucopyranosyl-3 - hydroxy-1α,5α,7α H- guaia-4(15),10(14),11(13)- trien-12,6α-olide (Ⅳ).Conclusion  Three flavonoid glycoside compounds and one sesquiterpenoid glycoside compound are isolated,and the flavonoid glycosides are isolated from Scorzonera ruprechtiana Lipsch.et Krasch.and also from Scorzonera genus plants for the first time.

Key words:  Scorzonera ruprechtiana;flavonoid glycoside;sesquiterpenoid glycoside