Abstract:

Abstract:Objective To analyze and evaluate the applications of diffusion tensor imaging(DTI) and diffusion weighted imaging(DWI) in cerebral infarction. Methods 84 cases with different phases cerebral infarction（6 cases in super-acute,30 cases in acute,26 cases in sub-acute and 22 cases in chronic phase） were performed by routine MRI,DWI and DTI scan,apparent diffusion coefficient (ADC),fractional anisotropy (FA) and the signal changes of DWI of the leision and the conlateral side were calculated and compared;The relationships among DWI,FA and ADC in different phases of cerebral infarction were analyzed. Results The leisons of super-acute and acute cerebral infarction showed obviously high signal on DWI images,and low signal in chronic cerebral infarction.The mean relative  ADC  (rADC) values of sub-acute and chronic cerebral infarction were higher than those of super-acute and acute cerebral infarction（P<0.05）.The FA values in 45 cases with different phases cerebral infarction (4 cases in super-acute,16 cases in acute,14 cases in sub-acute and 11 cases in chronic phase)  were all lower than those in conlateral regions（P<0.05）.Conclusion DWI and DTI can detect super-acute and acute lesions,the combination of DWI and conventional MRI can differentiate the phases of cerebral infarction.

Key words: magnetic resonance imaging;diffusion;diffusion tensor;cerebral infarction