Journal of Jilin University Medicine Edition

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Detection of serum levels of hypersensitivity C-reactive 
protein in patients with essential hypertension and 
periodontitis and clinical significance

LIU Yan,WANG Lei,LIN Chong-tao,REN Chun-xia,DING Zi-qing,TANG Yu-xin,YU Hai-jiao   

  1. Department of Periodontology,Stomatology Hospital,Jilin University,Changchun
     130021,China
  • Received:2012-12-28 Online:2013-07-28 Published:2013-08-17

Abstract:

Abstract:Objective To detect the periodontal status and the serum levels of h
ypersensitivity C reactive protein (hs-CRP) in the patients with chronic
  periodontitis and essential  hypertension,the patients with single chronic per
iodontitis and healthy subjects,and to explore relationship between chronic periodontitis and essential hypertension.
Methods There were 32 patients with chronic periodontitis and essential hypertension,38 patients with chronic
periodontitis and 34 healthy controls.The clinical periodontal parameters including plaque index(PLI),probing depth(PD),attachment loss(AL) and bleeding inde
x(BI) were examined,and the serum levels of hs-CRP were tested.Results Compared with healthy group and chronic periodontitis group,the PD,AL and BI in chronic periodontitis and essential hypertension group were significantly increased (P<0.05).The hs-CRP level of  the patients in chronic periodontitis and essential hypertension group was significantly higher than those in chronic periodontitis group and healthy group (P<0.05),and the hs-CRP level of the patients  in
chronic periodontitis group was significantly higher than that in healthy group (P<0.05).Conclusion Hypertension might increase the severity of chronic periodontitis,and  chronic periodontitis may increase the level of serum hs-CRP in patients with hypertension.

Key words: periodontitis, essential hypertension, C-reactive protein

CLC Number: 

  • R544.1