Abstract:

Objective
 To prepare nanofiber dressing by using electrospinning technology and determine its bacteriostatic efficacy. Methods Polyacrylonitrile (PAN) was used for precursor,by applying electrostatic spinning technology and high temperature carbonization method carbon nanofibers were prepared.Useing silver mirror reaction,nanoscale silver / carbon nanofiber composite dressing was prepared.According to Kirby-Baucer method,antibacterial extrasomatic test was conducted with these two samples and gentamicin scraps of paper and urgotul.Results The composite dressing had nanofiber scaffold structure and carried anoscale silver.The in  vitro antibacterial experiment results showed that the nanoscale silver / carbon nanofiber composite dressing and urgotul had good antimicrobial effects on  Staphylococcus aureus(Pae),E.coli(Eco) and Pseudomonas aeruginosa(Sau);the effects of composite dressing were  better than urgotul on Pae and Sau,but was poor on Eco(P<0.05);the carbon nanofiber dressing had no antibacterial property.Conclusion The nanoscale silver / carbon nanofiber composite dressing with  nanofiber scaffold structure and good antimicrobial effect is a good burn wound dressing.

Key words: carbon fiber；nanoscale silver；dressing；antibacterial test