Abstract:

Objective To study the feasibility of vertebral internal fixation using deer as animal models by comparing the biological parameters of deer,sheep and human lumbar and to provide the morphological parameters,the bone density,and the  biomechanical data of laboratory animals for related medical research.Methods 10 sets of fresh sika deer lumbar,10 sets of fresh sheep lumbar,and 10 sets of fresh lumbar of male cadavers were selected as the materials.The morphological observation of the lumbar vertebral bodies and pedicles of  three groups were taken,and the cancellous bone density,ultimate stress and elastic modulus   were measured and compared.Results There were significant differences of heights of right vertebral pedicles between three groups(P<0.01);the deer had the largest one,the sheep followed,and the human had the smallest one.There were remarkable differences of the widths of right vertebral pedicles and anterior disc heights between three groups（P<0.05）;the human had  the largest one,the deer followed,and the sheep had the smallest one.There were significant differeces of apparent density,elastic modulus and ultimate stress between three groups(P<0.05);the  sheep had the largestone,the deer followed,and the human had  the smallest one.Conclusion Deer lumbar is more similar as that of human according to  anatomic form and biomechanics compared with  the sheep lumbar.Therefore,deer is a more suitable to set up animal model for ve
rtebral internal fixation research.