A total of 56 patients with peri-implantitis were divided into two groups according to the voluntary principle： control group（n=30） and traditional Chinese medicine group（n=26）. There were no significant differences in the age，sex， probing depth （PD），modified plaque index （mPLI） and modified sulcus bleeding index （mSBI） and the level of interleukin-6（IL-6） in peri-implant sulcular fluid （PISF） before treatment of the patients in two groups（P>0.05）；the data was comparable. After basic periodontal treatment， in traditional Chinese medicine group distilled water was replaced in the EMS subgingival sandblast machine with honeysuckle and forsythia suspense extract for glycine subgingival sandblasting； in control group the patients received subgingival sandblast with glycine granules and distilled water. The PD， mPLI and mSBI of the affected teeth of the patients in two groups were recorded at 1，2 and 4 weeks after treatment. Enzyme-linked immunosorbent assay （ELISA） was used for the detection of IL-6 in PISF of the patients in two groups.

The levels of IL-6， mPLI and mSBI of the patients in two groups after treatment were lower than before treatment and the indexes in traditional Chinese medicine group mentioned above were decreased more obviously than control group （P<0.05）.

Glycine subgingival sandblast combined with basic periodontal treatment has a good therapeutic effect on the peri-implantitis； honeysuckle and forsythia suspense extract has a good promotion effect.