Journal of Jilin University(Engineering and Technology Edition) ›› 2022, Vol. 52 ›› Issue (10): 2419-2427.doi: 10.13229/j.cnki.jdxbgxb20210278

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Detecetion of lung nodule based on mask R-CNN and contextual convolutional neural network

Xiao-ying PAN1,2(),De WEI1,2,Yi-zhe ZHAO1,3   

  1. 1.School of Computer Science and Technology，Xi'an University of Posts and Telecommunications，Xi'an 710121，China
    2.Key Laboratory of Network Data Analysis and Intelligent Processing of Shaanxi Province，Xi'an 710121，China
    3.School of Information Science and Technology，Northwest University，Xi'an 710129，China
  • Received:2021-04-01 Online:2022-10-01 Published:2022-11-11

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Abstract:

In order to improve the effect of early lung cancer diagnosis， a pulmonary nodule detection algorithm based on deep learning architecture is proposed. A Mask R-CNN pulmonary nodule detection module based on V-Net & R-CNN， and a false-positive attenuation network for pulmonary nodules based on multi-scale and context are designed. The algorithm first uses V-Net for lung nodule localization， and then uses 3D R-CNN for false positive attenuation to determine whether the candidate region is a real lung nodule. Among them， the Inception network is introduced to design a V-Net multi-scale module to realize the localization of pulmonary nodules. A 3D R-CNN pulmonary nodule detection model was designed， and the lung nodule localization results were fused to determine the candidate regions of false-positive pulmonary nodules. The false positive attenuation network classification model designed by the design realizes the false positive judgment of lung nodules and improves the detection effectiveness. The experimental results showed that the algorithm achieves a FROC value of 0.97， which was 5% higher than that of the existing algorithms， indicating that the algorithm has good clinical significance for early detection and diagnosis of lung cancer.

Key words: computer application, lung nodule detection, convolutional neural network, recurrent neural network, multi-scale feature fusion, context convolution

CLC Number: 

  • TP391

Fig.1

3D Inception multi-scale block"

Fig.2

Multi-scale 3D V-Net model"

Fig.3

Workflow of R-CNN algorithm"

Fig.4

Conversion of 2D lung nodule candidate bounding box to 3D candidate bounding box"

Fig.5

False-positive reduction model"

Fig.6

Contextual false-positive reduction model"

Table 1

Model performance of lung nodule false-positive reduction model"

学习率DropoutF1?Score准确率/%
1e-40.50.96496.4
1e-40.80.97193.6
1e-60.50.97998.3
1e-60.80.96896.3

Fig.7

Training model of lung nodule false-positive reduction"

Fig.8

Segmentation results of the lung parenchyma"

Fig.9

Lung nodule segmentation results obtained by multiscale 3D V-Net"

Fig.10

Results of selective search in 2D lung slices"

Fig.11

Line chart for model performance of lung nodule false-positive reduction models"

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