To actively control the development and evaporation processes of the wall-impinging sprays, the metal surfaces with different microstructures and wettability were prepared with various methods. The morphological development processes of diesel and n-butanol sprays after hitting the surfaces under different surface wettability, wall temperatures and ambient back pressures were investigated based on a high-speed photography platform. The results show that increasing the roughness of the oleophilic surfaces can enhance the oleophilicity of the surfaces. The oleophilicity of the surfaces can be significantly reduced with the method of surface free energy modification. As the oleophilicity of the surfaces decreases, the spreading radius and the entrainment height of the fuel sprays after hitting the surfaces increase. Compared with diesel droplets, n-butanol droplets have a stronger wetting ability to surfaces, resulting in a smaller spreading range of n-butanol sprays after hitting different surfaces. Compared to n-butanol, the surface temperature has less influence on the spreading radius of the diesel sprays. The spreading radii of the diesel sprays are higher than 40 mm at the later stage after hitting the walls with different temperatures. The increasing ambient back pressure has an inhibitory effect on the diffusion of the sprays.