吉林大学学报(医学版) ›› 2021, Vol. 47 ›› Issue (2): 483-488.doi: 10.13481/j.1671-587X.20210230

• 临床医学 • 上一篇    下一篇

金银花连翘提取液联合甘氨酸喷砂治疗种植体周围炎的疗效评价

黄玉1,仲杨1,赵竹兰2,张庆宇2,夏德庚1,张莉2(),马宁1()   

  1. 1.吉林大学口腔医院牙周科,吉林 长春 130021
    2.吉林大学口腔医院急诊科,吉林 长春 130021
  • 收稿日期:2020-09-01 出版日期:2021-03-28 发布日期:2021-03-25
  • 通讯作者: 张莉,马宁 E-mail:2239003764@qq.com;maningbsh76@sina.com
  • 作者简介:黄 玉(1995-),女,河南省潢川县人,在读硕士研究生,主要从事牙周病基础与临床方面的研究。
  • 基金资助:
    吉林省中医药管理局中医药科技项目(2020129)

Evaluation on efficacy of honeysuckle and forsythia suspense extract combined with glycine sandblast in treatment of peri-implantitis

Yu HUANG1,Yang ZHONG1,Zhulan ZHAO2,Qingyu ZHANG2,Degeng XIA1,Li ZHANG2(),Ning MA1()   

  1. 1.Department of Periodontology,Stomatology Hospital,Jilin University,Changchun 130021,China
    2.Department of Emergency,Stomatology Hospital,Jilin University,Changchun 130021,China
  • Received:2020-09-01 Online:2021-03-28 Published:2021-03-25
  • Contact: Li ZHANG,Ning MA E-mail:2239003764@qq.com;maningbsh76@sina.com

摘要: 目的

观察甘氨酸喷砂对种植体周围炎的作用,探讨金银花连翘提取液用于甘氨酸龈下喷砂治疗种植体周围炎的辅助作用,分析复合中药治疗种植体周围炎的可行性。

方法

将56例种植体周围炎患者按照自愿原则分为对照组(n=30)和中药组(n=26),2组患者年龄、性别以及治疗前受试种植牙位探诊深度(PD)、改良菌斑指数(mPLI)、改良龈沟出血指数(mSBI)和种植牙周袋龈沟液(PISF)中白细胞介素6(IL-6)水平比较差异无统计学意义(P>0.05),具有可比性。2组患牙均进行牙周基础治疗后,中药组将EMS喷砂机中的蒸馏水替换为金银花连翘提取液进行甘氨酸龈下喷砂;对照组进行甘氨酸颗粒和蒸馏水龈下喷砂。治疗后第1、2和4周记录2组患者种植牙位PD、mPLI和mSBI。酶联免疫吸附试验(ELISA)法检测2组患者PISF中IL-6水平。

结果

治疗后,中药组和对照组患者PD、PISF中IL-6水平、mPLI和mSBI评分均较治疗前降低,且中药组较对照组降低更明显(P<0.05)。

结论

在牙周基础治疗上进行甘氨酸喷砂对种植体周围炎有良好的治疗效果,金银花连翘提取液对该治疗效果有较好的促进作用。

关键词: 金银花, 连翘, 甘氨酸喷砂, 种植体周围炎

Abstract: Objective

To observe the effect of glycine sandblast on peri-implantitis and investigate the assistant effect of honeysuckle and forsythia suspense extract combined with glycine subgingival sandblast in the treatment of peri-implantitis, and to analyze the feasibility of compound Chinese medicine in the treatment of peri-implantitis.

Methods

A total of 56 patients with peri-implantitis were divided into two groups according to the voluntary principle: control group(n=30) and traditional Chinese medicine group(n=26). There were no significant differences in the age,sex, probing depth (PD),modified plaque index (mPLI) and modified sulcus bleeding index (mSBI) and the level of interleukin-6(IL-6) in peri-implant sulcular fluid (PISF) before treatment of the patients in two groups(P>0.05);the data was comparable. After basic periodontal treatment, in traditional Chinese medicine group distilled water was replaced in the EMS subgingival sandblast machine with honeysuckle and forsythia suspense extract for glycine subgingival sandblasting; in control group the patients received subgingival sandblast with glycine granules and distilled water. The PD, mPLI and mSBI of the affected teeth of the patients in two groups were recorded at 1,2 and 4 weeks after treatment. Enzyme-linked immunosorbent assay (ELISA) was used for the detection of IL-6 in PISF of the patients in two groups.

Results

The levels of IL-6, mPLI and mSBI of the patients in two groups after treatment were lower than before treatment and the indexes in traditional Chinese medicine group mentioned above were decreased more obviously than control group (P<0.05).

Conclusion

Glycine subgingival sandblast combined with basic periodontal treatment has a good therapeutic effect on the peri-implantitis; honeysuckle and forsythia suspense extract has a good promotion effect.

Key words: honeysuckle, forsythia suspense, glycine sandblast, peri-implantitis

中图分类号: 

  • R781.4