吉林大学学报(医学版)

• 基础研究 • 上一篇    下一篇

不同评分模型对短暂性脑缺血发作后脑梗死的风险预测价值

王莹莹,郭 娜,何金婷,邵延坤,包晓群,莽 靖,徐忠信   

  1. 吉林大学中日联谊医院神经内科,吉林 长春130033
  • 收稿日期:2014-03-04 出版日期:2014-07-28 发布日期:2015-01-18
  • 通讯作者: 莽 靖(Tel:0431-84995820,E-mail:mangjing@jlu.edu.cn);  徐忠信(Tel:0431-84995998,E-mail:xuzhongxin999@aliyun.com) E-mail:mangjing@jlu.edu.cn; xuzhongxin999@aliyun.com
  • 作者简介:王莹莹(1989-),女,吉林省通化市人,在读医学硕士,主要从事脑血管 病的临床研究。
  • 基金资助:

     吉林省科技厅科技发展计划项目资助课题(20130206045SF)

Risk prediction values of  different  score models for cerebral 
infarction  after transient ischemic attack

WANG Ying-ying,GUO Na,HE Jin-ting,SHAO Yan-kun,BAO Xiao-qun,MANG Jing,
XU Zhong-xin   

  1. Department of Neurolrogy,China-Japan Union Hospital,Jilin University,Changchun 130033,China
  • Received:2014-03-04 Online:2014-07-28 Published:2015-01-18

摘要:

目的:评估ABCD、ABCD2、SPI-Ⅱ和ESSEN风险预测评分模型对短暂性脑缺血发作(TIA)高危患者近期及远期进展为脑梗死的预测价值。方法:回顾性分析235例TIA患者ABCD、ABCD2、SPI-Ⅱ和ESSEN评分,随访7 d和1年内脑梗死发生率,通过绘制受试者工作特征曲线(ROC)并计算曲线下面积(AUC)以评估4种评分模型的准确性,并与原始模型进行比较,计算相对危险度(RR)。 结果:235例TIA 患者7 d内脑梗死发生率为9.36%,1年内脑梗死发生率为20.43% 。7 d内AUC,ABCD评分模型为0.70,ABCD2评分模型为0.74,SPI-Ⅱ评分模型为0.67,ESSEN评分模型为0.62;1年内AUC,ABCD评分模型为0.62,ABCD2评分模型为0.62,SPI-Ⅱ评分模型为0.64,ESSEN评分模型为0.65。与原始模型比较,低危组、中危组和高危组患者TIA后7 d内RR值, ABCD评分模型分别为 0.09、0.92和0.72,ABCD2评分模型分别为0.49、0.59和0.65;TIA后1年内RR值,SPI-Ⅱ评分系统分别为0.58、0.87和0.55,ESSEN评分模型分别为0.11、0.18和0.55。 结论:本研究选择的4种风险预测评分模型均可用于中国人群TIA后脑梗死风险评估,其中ABCD2评分模型对短期风险预测具有较大价值,而ESSEN评分模型对于远期风险预测更具价值。

关键词: 危险性评估, 短暂性脑缺血发作, 脑梗死

Abstract:

Abstract:Objective To evaluate the predictive values of ABCD,ABCD2,SPI-Ⅱ and ESSEN score
 models for the patients with   high-risk transient ischemic attack(TIA)  to develop to  cerebral infarction in short and long term.
Methods The   ABCD,ABCD2,SPI-Ⅱ and ESSEN scores of  235 cases of TIA patients were retrospectively analyzed.The incidence
of cerebral infarction was followed up for 7 d and 1 year,and the receiver operating characteristic curve (ROC) was drawn to calculate the area under  curve(AUC) to assess the accuracy of the score models,and compared with the original model and  the relative risk(RR) value was calculated.Results The 7 d-incidence and 1 year-incidence of cerebral infarction in the 235 TIA patients were 9.36 % and 20.43%.The AUC of ABCD,ABCD2, SPI-Ⅱ and ESSEN models for 7 d were 0.70,
0.74,0.67, and 0.62.The  AUC of 1 year were 0.62,0.62,0.64, and 0.65.Compared with the orginal models,the RRs for 7 d of ABCD score model of the TIA patients in low,middle,and high risk groups were 0.09,0.92,and 0.72;the RRs of ABCD2 score model were 0.49,0.59,and 0.65;the RRs of SPI-Ⅱ score model were 0.58,0.
87, and 0.55;the RRs of ESSEN score model were 0.11,0.18,and 0.55.Conclusion ABCD,ABCD2,SPI-Ⅱ and ESSEN score models
 can be  used to assess the risk of cerebral infarction after TIA in Chinese population.The  ABCD2 score model is of great value for short-term risk prediction,and the ESSEN score model is more value for long-term risk prediction.

Key words: risk assessment, transient ischemic attack , cerebral infarction

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