关键词: 早期经口进食, 腹腔镜手术, 结直肠肿瘤, 卡氏评分, 胃肠道生存质量

Abstract:

Abstract:Objective To investigate the influence of early oral feeding (EOF) after laparoscopic surgery in the function status and gastrointestinal living qualit
y of the patients with colorectal cancer,and to clarify the feasibility of EOF after laparoscopic surgery.Methods Sixty-three patients underwent laparoscopic s
urgery of colorectal cancers participated in the trial.Of these,31 patients received EOF as EOF group,received a clear liquid diet on the first postoperative
 day followed by a regular diet as tolerated;the other 32 patients received traditional oral feeding (TOF) as TOF group who were fed with feeding only after the
 recovery of their postoperative gastrointestinal functions.The nasogastric tube was removed from all patients in both groups immediately after surgery.
Self-designed EOF questionnaire data,Karnofsky Scores and Gastrointestinal Quality of Life Index(GIQLI) Scores were used to evaluate the functional status and gastrointestinal living guality of the patients.Results The using time of  total parenteral nutrition (TPN)，time of postoperative hospital stay，and costs after surgery in EOF group were lower than those in TOF group(P<0.05);but there were no significnat differences in the  first passage of flatus and feces time between two groups(P<0.05)，also there were no significant differences in the incidence of nasogastric tube reinsertion,pulmonary infection,intestinal obstruction,balance of intestinal bacteria,fistula，incision infection between two groups (P>0.05)，and the incidence of abdominal distension was higher than that in TOF group（P<0.05）；on postoperative day 7，the albumin recovered faster in  EOF group（P<0.05），and on postoperative day 4 and 7，the pro-albumin also recovered faster in  EOF group（P<0.05）；the patients in EOF group had a higher Karnofsky score（P<0.05） and GIQLI score compared with the patients in TOF group（P<0.05）.Conclusion EOF after laparoscopic surgery in the patients with  colorectal cancers is beneficial for rehabilitation,and it can reduce the risk of hospitalization and saving its costs；it plays an active role in protein recovery，and  improves the functional status and gastrointestinal living quality of the patients.

Key words: early oral feeding；laparoscopic , surgery；colorectal neoplasms；Karnofsky Score；gastrointestinal living quality