体质状况对肺炎心衰患儿血清肌钙蛋白I水平的影响及其临床意义

doi:10.13481/j.1671-587x.20160323

吉林大学学报(医学版) ›› 2016, Vol. 42 ›› Issue (03): 541-544.doi: 10.13481/j.1671-587x.20160323

体质状况对肺炎心衰患儿血清肌钙蛋白I水平的影响及其临床意义

汪玉堂¹, 韦祁山², 张月霞², 马长寿³

1. 西北民族大学医学院人体解剖教研室, 甘肃兰州 730030;
2. 甘肃省兰州市妇幼保健院儿科, 甘肃兰州 730030;
3. 甘肃省临夏州人民医院骨科, 甘肃临夏 731100

收稿日期:2015-04-27 发布日期:2016-06-17
通讯作者: 韦祁山,主任医师(Tel:0931-8117262,E-mail:sqw937@126.com) E-mail:sqw937@126.com
作者简介:汪玉堂(1963-),男,甘肃省兰州市人,教授,医学硕士,主要从事体质人类学方面的研究。
基金资助:
国家民委科研项目资助课题(14XBZ023);甘肃省兰州市科技计划项目资助课题(2012-1-15)

Effect of physical constitution on serum cTnIlevel in children with pneumonia complicated by heart failure and its clinical significance

WANG Yutang¹, WEI Qishan², ZHANG Yuexia², MA Changshou³

1. Department of Anatomy, College of Medical Sciences, Northwest University For Nationalities, Lanzhou 730030, China;
2. Department of Pediatrics, Lanzhou Maternity and Child-Care Hospital, Gansu Province, lanzhou 730030, China;
3. Department of Orthopaedics, People's Hospital of Linxia State, Gansu Province, Linxia 731100, China

Received:2015-04-27 Published:2016-06-17

摘要/Abstract

摘要：

目的: 探讨体质对肺炎心衰患儿血清肌钙蛋白I(cTnI)水平的影响,并评估其临床价值。方法: 选择1~3岁肺炎心衰患儿116例作为观察组,并选择同期行正常体检的1~3岁儿童98人作为对照组。测量观察对象的身高、体质量,根据幼儿Kaup指数将2组研究对象为正常组(Kaup指数为13.5~18.0kg·cm^-2)、优良组(Kaup指数为18.1~20.0kg·cm^-2)及肥胖组(Kaup指数>20.0kg·cm^-2)。测定各组受试者血清cTnI和超敏C反应蛋白(hsCRP)水平,并分析血清cTnI和hsCRP水平与Kaup指数的相关性。结果: 观察组患儿血清cTnI和hsCRP水平均高于对照组(P=0.000),血清cTnI和hsCRP水平随Kaup指数水平升高而逐渐升高,血清cTnI和hsCRP水平与Kaup指数水平呈正相关关系(r=0.555,P=0.000;r=0.705,P=0.000),血清cTnI与hsCRP水平亦呈正相关关系(r=0.407,P=0.000)。结论: 体质状况明显影响肺炎心衰患儿血清cTnI水平,Kaup指数高者其血清cTnI和hsCRP水平亦高,因此单纯依赖cTnI水平检查不利于肥胖肺炎患儿心衰的诊断和预后判断。

关键词: 肌钙蛋白I, Kaup指数, 肺炎, 心力衰竭

Abstract:

Objective: To explore the effect of physical constitution on the serum cardiac troponin I(cTnI) level in the children with pneumonia complicated by heart failure,and to assess its clinical value. Methods: Atotal of 116 patients aged 1-3 years with pneumonia complicated by heart failure were enrolled in this study as observation group,and 98 healthy children aged 1-3 years were enrolled as control group.The height and weight of each subject were measured,and the infant Kaup index was calculated with these parameter.The subjects in two groups were divided into 3 subgroups according to the Kaup index: normal group (Kaup index 13.5-18.0 kg·cm^-2),excellent group(Kaup index 18.1-20.0 kg·cm^-2),and obese group(Kaup index>20.0 kg·cm^-2).The levels of serum cTnI and hsCRP of subjects were detected, respectively,and the relationship between the levels of serum cTnI,hsCRP and Kaup index was analyzed. Results: The levels of serum cTnI and hsCRP of the subjects in observation group were significantly higher than those in control group (P=0.000),and they were increased with the increasing of Kaup index,and they were positively correlated with Kaup index(r=0.555,P=0.000;r=0.705,P =0.000).The level of serum cTnI was positively correlated with the level of serum hsCRP(r=0.407,P=0.000). Conclusion: In the children with pneumonia complicated by heart failure,the serum cTnI level is affacted significantly by physical constitution,and the levels of serum cTnI and hsCRP are high if the Kaup index of subject is high,so relying only on the level of serum cTnI is not conducive to the diagnosis and prognosis for the obesity patients with pneumonia complicated by heart failure.

Key words: cardiac troponin I, Kaup index, pneumonia, heart failure

中图分类号:

R563.1

汪玉堂, 韦祁山, 张月霞, 马长寿. 体质状况对肺炎心衰患儿血清肌钙蛋白I水平的影响及其临床意义[J]. 吉林大学学报(医学版), 2016, 42(03): 541-544.

WANG Yutang, WEI Qishan, ZHANG Yuexia, MA Changshou. Effect of physical constitution on serum cTnIlevel in children with pneumonia complicated by heart failure and its clinical significance[J]. Journal of Jilin University Medicine Edition, 2016, 42(03): 541-544.

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体质状况对肺炎心衰患儿血清肌钙蛋白I水平的影响及其临床意义

Effect of physical constitution on serum cTnIlevel in children with pneumonia complicated by heart failure and its clinical significance

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