吉林大学学报(医学版) ›› 2017, Vol. 43 ›› Issue (03): 622-625.doi: 10.13481/j.1671-587x.20170330

• 临床医学 • 上一篇    下一篇

腹股沟疝无张力修补术患者预防性应用抗生素的临床观察及其意义

石俊忠, 庄建彬, 孙惠军, 陈玉琢, 宋维亮, 孟祥朝   

  1. 天津市第三中心医院普外科, 天津 300170
  • 收稿日期:2016-11-12 出版日期:2017-05-28 发布日期:2017-06-01
  • 通讯作者: 石俊忠,副教授,副主任医师(Tel:022-84112181,E-mail:871655161@qq.com) E-mail:871655161@qq.com
  • 作者简介:石俊忠(1963-),男,天津市人,副教授,副主任医师,主要从事甲状腺乳腺、疝外科和胃肠肿瘤外科临床治疗方面的工作。
  • 基金资助:
    天津市卫计委重点攻关项目资助课题[15KG116(2016-06)]

Clinical observation of preventive use of antibiotic inguinal hernial repair without tension and its significance

SHI Junzhong, ZHUANG Jianbin, SUN Huijun, CHEN Yuzhuo, SONG Weiliang, MENG Xiangchao   

  1. Department of General Surgery, Tianjin Third Central Hospital, Tianjin 300170, China
  • Received:2016-11-12 Online:2017-05-28 Published:2017-06-01

摘要: 目的:探讨腹股沟疝无张力修补术中预防性使用抗生素的必要性及年龄和手术时间对疗效的影响,阐明腹股沟疝无张力修补术中合理应用预防性抗生素的临床意义。方法:选择择期行腹股沟疝无张力修补患者228例,其中42例患者具有高危感染因素预防性使用抗生素(使用抗生素组),186例患者围手术期未预防性使用抗生素(未使用抗生素组)。预防性抗生素于手术切皮前30min给予,术后常规剂量使用不超过48h。手术均使用人工修补材料行无张力疝修补术。记录使用抗生素组和未使用抗生素组患者年龄、术后最高体温、白细胞计数、手术耗时、术后住院时间和术后体温,并进行统计学分析。结果:未使用抗生素组年龄<60岁患者手术前后白细胞数多于年龄≥60岁患者(P<0.05),但手术时间、术后住院时间和体温比较差异无统计学意义(P>0.05);与手术时间>90min患者比较,手术时间≤90min患者手术前后白细胞计数升高,住院时间延长(P<0.05),但年龄和术后体温比较差异无统计学意义(P>0.05)。使用抗生素组和未使用抗生素组患者手术前后白细胞计数、手术时间、住院时间和术后体温比较差异无统计学意义(P>0.05)。结论:大多数择期腹股沟疝无张力修补术中不使用抗生素和对高危感染患者的预防性使用抗生素均可使患者安全地接受和完成疝修补。

关键词: 抗生素, 腹股沟疝, 无张力疝修补, 预防性使用

Abstract: Objective: To explore the necessity of the preventive use of antibiotics and the effects of age and operation time on the efficacy of inguinal hernia repair without tension, and to elucidate the clinical significance of the preventive application of prophylactic antibiotics in inguinal hernia repair without tension. Methods: A total of 228 patients with inguinal hernia repair without tension were selected, amomg them 42 cases with high infection factors were treated with antibiotics (treated group),and 186 cases were not treated with antibiotics(untreated group) during the preoperative period.The prophylactic antibiotics were given 30 min before surgery, and the conventional dose was not used more than 48 h after surgery. All the cases were treated with artificial repair materials for the procedure of inguinal hernialrepair without tension.The age, highest body temperature, white blood cell count, operation time, hospitalization time, and postoperative body temperature of all the 228 cases were recorded and analyzed statistically. Results: The preoperative and postoperative white blood cell counts had significant differences between the patients<60 years and the patients ≥ 60 years in untreated group (P<0.05);there were no significant differences in the operation time, hospitalization time and body temperature between the patients<60 years and the patients ≥ 60 years in untreated group (P>0.05).Compared with the patients with the operation time>90 min, the white blood cell count and hospitalization time of the patients with the operation time ≤ 90 min were increased (P<0.05).There were no significant differences of the body temperature and age between the patients with the operation time >90 min and the patients with the operation time ≤ 90 min (P>0.05). The white blood cell count, operation time,hospitalization time and postoperative body temperature of the patients between treated group and untreated group had no significant differences (P>0.05). Conclusion: The use of antibiotics in the high-risk patients and non-use of antibiotics in the majority of elective inguinal hernia repair without tension can ensure the safe and performability of the patients.

Key words: inguinal hernia, tension-free repair, antibiotic, preventive use

中图分类号: 

  • R656.21