吉林大学学报(医学版) ›› 2018, Vol. 44 ›› Issue (04): 825-827.doi: 10.13481/j.1671-587x.20180425

• 临床医学 • 上一篇    下一篇

皮肤转移癌伴发带状疱疹1例报告并文献复习

李晓1, 邱香2, 马振卉1, 田亚萍1   

  1. 1. 吉林大学第一医院皮肤性病科, 吉林 长春 130021;
    2. 吉林大学第一医院放射线科, 吉林长春 130021
  • 收稿日期:2017-12-03 出版日期:2018-07-28 发布日期:2018-07-27
  • 通讯作者: 田亚萍,副教授,硕士研究生导师(Tel:0431-88782663,E-mail:yapingtian@163.com) E-mail:yapingtian@163.com
  • 作者简介:李晓(1992-),女,山东省滨州市人,在读医学硕士,主要从事皮肤性病学方面的研究。
  • 基金资助:
    吉林省教育厅"十二五"科学技术研究项目资助课题(2015-515)

Skin metastatic carcinoma complicated with herpes zoster:A case report and literature review

LI Xiao1, QIU Xiang2, MA Zhenhui1, TIAN Yaping1   

  1. 1. Department of Dermatology and Venerology, First Hospital, Jilin University, Changchun 130021, China;
    2. Department of Radiology, First Hospital, Jilin University, Changchun 130021, China
  • Received:2017-12-03 Online:2018-07-28 Published:2018-07-27

摘要: 目的:探讨皮肤转移癌的临床特点,为其临床诊治提供参考。方法:分析1例皮肤转移癌伴发带状疱疹患者的临床资料,并复习相关文献。患者4个月前右胸壁出现红斑、水疱伴疼痛,于当地医院诊断为"带状疱疹"并给予相关治疗,疼痛好转,局部仍有红斑、丘疹和结节;20 d前皮损出现破溃、糜烂,并迅速扩大加深,就诊于本院行病理检查及肺CT和全腹CT等其他辅助检查。结果:皮损穿刺病理检查诊断为浸润性癌,伴广泛梗死;肺CT和全腹CT等检查显示,右侧乳腺占位性病变,并发颈部淋巴结、肝、胸膜和骨等多部位转移。给予局部治疗、多西他赛联合曲妥珠单抗化疗2个疗程后皮损情况改善,但未能完全愈合。结论:皮肤转移癌少见,临床表现多样。临床医生应掌握其发病规律,及时行组织病理检查和其他部位的相关检查,减少误诊和漏诊的发生。

关键词: 带状疱疹, 计算机X线断层成像术, 皮肤转移癌, 乳腺肿瘤

Abstract: Objective:To study the clinical features of skin metastatic carcinoma,and to provide the reference for its diagnosis and treatment. Methods:The clinical materials of one case of cutaneous metastases complicated with herpes zoster were analyzed and the related literatures were reviewed.The right chest wall in the patient appeared erythema and blisters with pain 4 months ago;in the local hospital the patient was diagnosed as herpes zoster and received relevant treatment;the pain was improved,but there were still erythema,papules and nodules in the local area.The skin lesions were erosive,expanded and deepened rapidly 20 days ago,and the pathological examination,lung CT,abdominal CT and other assistant examinations were performed in our hospital. Results:The lesion biopsy results showed invasive carcinoma with extensive infarction.The results of lung CT,abdominal CT and other assistant examinations showed the right breast occupying lesions complicated with cervical lymph nodes,liver,pleural and bone metastases.The skin lesions were improved after local treatment and 2 courses of chemotherapy(docetaxel combined with trastuzumab), but failed to heal completely. Conclusion: Skin metastatic carcinoma is rare,and its clinical manifestations are different.The clinicians should master the regularity of the disease,timely conduct the histopathological examination and the related examination in the other parts to reduce the incidence of misdiagnosis and missed diagnosis.

Key words: skin metastatic carcinoma, herpes zoster, computerized tomography,X-ray, breast neoplasms

中图分类号: 

  • R737.9