吉林大学学报(医学版) ›› 2019, Vol. 45 ›› Issue (06): 1445-1448.doi: 10.13481/j.1671-587x.20190643

• 临床医学 • 上一篇    下一篇

PET/CT影像诊断为肺癌性淋巴管炎的肺结节病1例报告及文献复习

刘伽莹, 田畅, 丛珊, 赵敏, 王珂   

  1. 吉林大学第二医院呼吸与危重症医学科, 吉林 长春 130041
  • 收稿日期:2019-03-06 出版日期:2019-12-05 发布日期:2019-12-05
  • 通讯作者: 王珂,教授,主任医师,博士研究生导师(Tel:0431-81136820,E-mail:kewangm1@hotmail.com) E-mail:kewangm1@hotmail.com
  • 作者简介:刘伽莹(1994-),女,吉林省四平市人,在读医学硕士,主要从事肺部感染性疾病和肺癌诊治方面的研究。
  • 基金资助:
    吉林省科技厅科技发展计划项目资助课题(20190303162SF,20180101103JC);吉林省科技厅科技发展计划项目医药健康专项资助课题(20191102012YY)

Pulmonary sarcoidosis diagnosed by PET/CT as pulmonary lymphangitic carcinomatosis: A case report and literature review

LIU Jiaying, TIAN Chang, CONG Shan, ZHAO Min, WANG Ke   

  1. Department of Respiratory and Critical Care Medicine, Second Hospital, Jilin University, Changchun 130041, China
  • Received:2019-03-06 Online:2019-12-05 Published:2019-12-05

摘要: 目的:探讨肺结节病的临床特点、诊断和治疗方法,提高临床医生对该疾病的认识。方法:收集1例肺结节病患者的临床资料、支气管镜和病理检查结果,并进行相关文献复习。结果:患者因咳嗽、渐进性呼吸困难2个月入院,查体未见明显阳性体征。胸部CT显示双肺多发结节影,双肺门及纵隔淋巴结肿大;PET-CT影像诊断为肺癌伴癌性淋巴管炎(PLC),双侧锁骨上、双肺门及纵隔淋巴结转移。入院后纤维支气管镜病理回报肺组织内见慢性肉芽肿性炎,未见明确坏死,不能完全排除结核。给予患者糖皮质激素和预防性抗结核治疗,1个月后复查胸部CT显示双肺结节明显减少,3个月后患者症状消失,胸部CT显示双肺结节基本消失,肺门和纵隔淋巴结明显缩小,最终诊断为肺结节病。结论:结节病的确诊应主要依据患者的病理诊断并结合临床表现,仅凭临床表现和影像学结果易误诊为肿瘤或者结核。

关键词: 结节病, 肺结节病, 病例报告, 癌性淋巴管炎

Abstract: Objective: To explore the clinical characteristics,diagnosis and treatment methods of pulomnary sarcoidosis,and to improve the clinicians' understanding of pulmonary sarcoidosis. Methods: The clinical materials,the results of bronchoscope and pathological examinations of one pulomnary sarcoidosis patient were collected,and the relative literatures were reviewed. Results: A patient with cough and progressive dyspnea for 2 months was admitted to the hospital,and the patient had no obvious positive signs. The chest CT images showed diffuse nodules in both lungs, bilateral hilar and mediastinal lymph node enlargement; lung cancer with pulmonary lymphangitic carcinomatosis(PLC),and metastasis of bilateral supraclavicular, bilateral hilar, mediastinal lymph nodes were diagnosed by PET-CT images.The pathological results of fiberoptic bronchoscope after hospitalization showed a chronic granulomatous inflammation in the lung tissue,without obvious necrosis, and tuberculosis could not be entirely excluded.The patients were given glucocorticoids and preventive anti-tuberculosis drugs; 1 month later, the chest CT showed a significant reduction in the bilateral pulmonary nodules; 3 months later, the symptoms of patient disappeared;the chest CT showed the biateral pulmonary nodules basically disappeared,the bilateral hilar and mediastinal lymph nodes were markedly shrunk;the pulmonary sarcoidosis was diagnosed finally. Conclusion: The diagnosis of pulomnary sarcoidosis should be mainly based on the pathological diagnosis combined with clinical manifestation of the patient;sarcoidosis is easily misdiagnosed as tumor or tuberculosis only by the clinical manifestations and the imaging results.

Key words: sarcoidosis, pulomnary sarcoidosis, case reports, pulmonary lymphangitic carcinomatosis

中图分类号: 

  • R563