女性不孕症患者弓形虫感染率及年龄分布

doi:吉林省科技厅资助课题（吉科合字第19980300

女性不孕症患者弓形虫感染率及年龄分布

李淑红^1*，戴培¹，崔黎明¹，宗珊¹，左文静²

1. 吉林大学基础医学院病原生物学教研室，吉林长春130021；2. 吉林大学基础医学院细胞生物学教研室，吉林长春130021

收稿日期:2005-03-21 修回日期:1900-01-01 出版日期:2006-01-28 发布日期:2006-01-28
通讯作者: 李淑红

Infection rate of Toxoplasma gondii and age distributionin female patients with sterility

LI Shu-hong^1*,DAI Pei¹,CUI Li-ming¹, ZONG Shan¹, ZUO Wen-jing²

1. Department of Pathogenobiology, School of Basic Medical Sciences, Jilin University, Changchun 130021,China； 2.Department of Cell Biology, School of Basic Medical Sciences, Jilin University, Changchun 130021,China

Received:2005-03-21 Revised:1900-01-01 Online:2006-01-28 Published:2006-01-28
Contact: LI Shu-hong

摘要/Abstract

摘要： 目的：探讨弓形虫感染与女性不孕症的关系。方法：采用酶联免疫吸附试验法，检测882例不孕症妇女（实验组）及107例正常孕产妇女（对照组）血清弓形虫抗体，进行不同年龄组间感染率差异的分析。结果：弓形虫抗体阳性率实验组（15.87%,140/882）高于对照组（5.61%，6/107）（P<0.01）。20～24岁、25～29岁、30～34岁、35～39岁和≥40岁年龄组感染率分别为15.63%、15.24%、17.91%、19.44%和15.38%，组间比较差异无显著性（P>0.05）。结论：不孕症妇女弓形虫感染没有年龄差异；弓形虫感染可能是不孕症的原因之一。

关键词: 女(雌)性, 弓形虫感染, 酶联免疫吸附测定

Abstract: Objective To discuss the relationship between the infection of Toxoplasma gondii and female sterility. Methods Toxoplasma gondii serum antibody were determined in 882 women with sterility (experimental group) and 107 normal bearing women (control group) by using ELISA. At the same time the differences of the infection with Toxoplasma gondii between the ages of the sterility women were analyzed. Results The positive rate in experimental group was 15.87% (140/882), the positive rate in control group was 5.61% (6/107), remarkable difference was found between two groups(P<0.01). The infection rate in the diffe rent age groups (20-24, 25-29,30-34,35-39 and ≥40) is 5.63%,15.24%,17.91%,19.44% and 15.38%. Conclusion Toxoplasma gondii infection may be one of the factors which can cause sterility, and the infection rates at different ages have no instinct differences.

Key words: female, Toxoplasma gondii infection, enzyme-linked immunosorbent assay

中图分类号:

R383.24

李淑红，戴培，崔黎明，宗珊，左文静. 女性不孕症患者弓形虫感染率及年龄分布[J]. J4, 2006, 32(1): 163-2.

LI Shu-hong,DAI Pei,CUI Li-ming, ZONG Shan, ZUO Wen-jing. Infection rate of Toxoplasma gondii and age distributionin female patients with sterility[J]. J4, 2006, 32(1): 163-2.

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