弥散加权和弥散张量成像在脑梗死诊断中的应用

J4 ›› 2009, Vol. 35 ›› Issue (4): 742-745.

弥散加权和弥散张量成像在脑梗死诊断中的应用

周宏伟, 兰文婧, 刘洋, 刘安, 谷艳英, 刘丹研, 许冰, 王军

吉林大学第一医院放射科|吉林长春 |130021

收稿日期:2009-02-07 出版日期:2009-07-28 发布日期:2009-08-24
通讯作者: 谷艳英 E-mail:zhw7734@sohu.com
作者简介:周宏伟（1977-）|男|吉林省长春市人|主治医师|在读医学博士|主要从事缺血性脑血管病功能成像的研究。
基金资助:
吉林省科技厅科研基金资助课题（200705132）；长春市科委科研基金资助课题（2006126）

Application |of DWI and DTI in diagnosis of cerebral infarction

ZHOU Hong-Wei, LAN Wen-Jing, LIU Yang, LIU An, GU Yan-Ying, LIU Dan-Yan, XU Bing, WANG Jun

Department of Radiology,First Hospital,Jilin University|Changchun 130021,China

Received:2009-02-07 Online:2009-07-28 Published:2009-08-24

摘要/Abstract

摘要：

目的：分析脑梗死的弥散张量成像(DTI)和弥散加权成像(DWI)的影像表现，评价其临床应用价值。方法：对84例不同时期（超急性期６例，急性期30例，亚急性期26例，慢性期22例）脑梗死患者行常规磁共振成像（MRI）、DWI及DTI扫描，比较患侧和健侧弥散信号的改变及表观弥散系数（ADC）、各项异性指数（FA）值的变化，分析不同时期脑梗死DWI信号改变、ADC值及FA值的关系。结果：超急性期、急性期和亚急性期病灶在DWI呈高信号，慢性期表现为低信号；亚急性期和慢性期平均相对表观弥散系数（rADC）值明显高于超急性期和急性期脑梗死病灶的平均rADC值（P<0.05）。45例不同时期（超急性期４例，急性期16例，亚急性期14例，慢性期11例）患者脑梗死区平均FA值明显低于健侧对应区的平均FA值（P<0.05）。结论：DWI和DTI可以快速检出超急性和急性期脑梗死，DWI和MRI的联合应用可以对脑梗死进行分期。

关键词: 磁共振成像;弥散;弥散张量;脑梗死

Abstract:

Abstract:Objective To analyze and evaluate the applications of diffusion tensor imaging(DTI) and diffusion weighted imaging(DWI) in cerebral infarction. Methods 84 cases with different phases cerebral infarction（6 cases in super-acute,30 cases in acute,26 cases in sub-acute and 22 cases in chronic phase） were performed by routine MRI,DWI and DTI scan,apparent diffusion coefficient (ADC),fractional anisotropy (FA) and the signal changes of DWI of the leision and the conlateral side were calculated and compared;The relationships among DWI,FA and ADC in different phases of cerebral infarction were analyzed. Results The leisons of super-acute and acute cerebral infarction showed obviously high signal on DWI images,and low signal in chronic cerebral infarction.The mean relative ADC (rADC) values of sub-acute and chronic cerebral infarction were higher than those of super-acute and acute cerebral infarction（P<0.05）.The FA values in 45 cases with different phases cerebral infarction (4 cases in super-acute,16 cases in acute,14 cases in sub-acute and 11 cases in chronic phase) were all lower than those in conlateral regions（P<0.05）.Conclusion DWI and DTI can detect super-acute and acute lesions,the combination of DWI and conventional MRI can differentiate the phases of cerebral infarction.

Key words: magnetic resonance imaging;diffusion;diffusion tensor;cerebral infarction

中图分类号:

R743.3

周宏伟, 兰文婧, 刘洋, 刘安, 谷艳英, 刘丹研, 许冰, 王军. 弥散加权和弥散张量成像在脑梗死诊断中的应用[J]. J4, 2009, 35(4): 742-745.

ZHOU Hong-Wei, LAN Wen-Jing, LIU Yang, LIU An, GU Yan-Ying, LIU Dan-Yan, XU Bing, WANG Jun. Application |of DWI and DTI in diagnosis of cerebral infarction[J]. J4, 2009, 35(4): 742-745.