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• 专题研究-体质人类学 •    下一篇

克里雅河下游地区封闭人群常染色体基因座D5S818、D7S820和D13S317遗传多态性

刘伟强1,2,崔银秋2,张全超1,周慧1,2,朱泓1   

  1. 1.吉林大学边疆考古研究中心古DNA实验室,吉林 长春 130012;2.吉林大学生命科学学院大分子实验室,吉林 长春 130023
  • 收稿日期:2006-02-21 修回日期:1900-01-01 出版日期:2007-01-28 发布日期:2007-01-28
  • 通讯作者: 周慧

Genetic polymorphisms of D5S818, D7S820 and D13S317 in isolated population in lower reaches of Keriyan River

LIU Weiqiang1,2, CUI Yinqiu2, ZHANG Quanchao1, ZHOU Hui1,2, ZHU Hong1   

  1. 1.Ancient DNA Laboratory,Research Center for Chinese Frontier Archaeology, Jilin University,Changchun 130012,China;2.Macromolecular Laboratory,College of Life Science, Jilin University, Changchun 130023,China
  • Received:2006-02-21 Revised:1900-01-01 Online:2007-01-28 Published:2007-01-28
  • Contact: ZHOU hui

摘要: 目的:研究克里雅封闭人群与新疆地区相关民族之间的相互关系。方法:以居住于塔克拉玛干沙漠中克里雅河下游地区封闭人群(80例)为研究对象,采用基因扫描技术对D5S818、D7S820和D13S317 3个常染色体STR基因座进行基因扫描,观察其遗传多态性。以Shriver的Dsw法计算克里雅封闭人群与相关人群之间的遗传距离,用NeighborJoining法构建系统发育树。结果:获得了克里雅封闭人群的D5S818、D7S820和D13S317 3个STR基因座等位基因频率;根据等位基因频率计算的群体之间遗传距离显示,克里雅封闭人群在D5S818、D5S820和D13S317 3个STR基因座上的遗传结构与新疆地区的乌兹别克族的遗传结构最为接近。结论:克里雅封闭人群与新疆地区的乌兹别克人群亲缘关系最近, 推测可能来源于相同的祖先群体。

关键词: STR, 多态性, 系统发育树

Abstract: Abstract:ObjectiveTo study the geneticrelationship between the isolated Keriyan population and ethnics in Xinjiang. Methods Three autosomal shorttandemrepeat (STR) polymorphisms (D5S818, D7S820 and D13S317) were analyzed by Genescan software in the isolated population in the center of Taklamakan desert of Xinjiang. Sheriver’s Dsw of the isolated population with others were estimated, and phylogenetic tree was constructed by using NeighborJoining method based on Dsw. Results Allelic frequencies of three autosomal STR were calculated, and the genetic distance based on allelic frequencies showed that the isolated population had the closest genetic distant with Uzbek of Xinjiang. ConclusionThe isolated population has the closest relationship with Uzbek, and they may be derived from the same ancestor.

Key words: STR, polymorphism, phylogenetic tree

中图分类号: 

  • Q987