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• 专题研究-体质人类学 • 上一篇    下一篇

内蒙古朱开沟遗址古代居民线粒体DNA分析

王海晶1,2,3，常娥1，蔡大伟1,3，张全超1 ，周慧1,3，朱泓1   

  1. 1.吉林大学边疆考古研究中心古DNA实验室，吉林 长春130012;2.吉林大学化学学院化学教学与研究中心，吉林 长春130012; 3.吉林大学生命科学学院大分子实验室，吉林 长春130023
  • 收稿日期:2006-02-21 修回日期:1900-01-01 出版日期:2007-01-28 发布日期:2007-01-28
  • 通讯作者: 周慧

Mitochondrial DNA analysis of remains from Zhukaigou archaeological site in Inner Mongolia

WANG Hai-jing1,2,3, CHANG E1, CAI Da-wei3, ZHANG Quan-chao3, ZHOU Hui1,3，ZHU Hong1   

  1. 1.Ancient DNA Laboratory,Research Center for Chinese Frontier Archaeology, Jilin University,Changchun 130012, China；2.Teaching and Research Center of Chemistry,College of Chemistry, Jilin University, Changchun 130021, China；3.Macromolecular Laboratory,College of Life Science, Jilin University, Changchun 130023, China)
  • Received:2006-02-21 Revised:1900-01-01 Online:2007-01-28 Published:2007-01-28
  • Contact: ZHOU Hui

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摘要： 目的：探讨内蒙古朱开沟古代居民的遗传关系。方法：对9例保存较好的个体牙齿的线粒体基因组的高可变一区进行扩增和测序，与内蒙古饮牛沟古代人群及现代亚洲人群对比进行系统发育分析，并推测单倍型类群归属。结果：获得7例朱开沟遗址古代居民线粒体基因组高可变一区364 bp的序列, 共检测出15个突变位点，界定7种单倍型，并归属到单倍型类群。结论：朱开沟古代居民在母系遗传上与其后的饮牛沟墓地古代居民及现代内蒙古地区人群关系密切，内蒙古中南部地区人群母系遗传结构具有连续性。

关键词: DNA, 线粒体, 古DNA, 系统发育分析

Abstract: Abstract:ObjectiveTo assess the genetic affinities of the population from the Zhukaigou archaeological site in Inner Mongolia. MethodsThe mitochondrial DNA hypervariable region Ⅰ (HVRⅠ) in teeth of 9 individuals were amplified and sequenced. Different phylogenetic analyses were performed using mtDNA sequences among the ancient population，the Yinniugou ancient population and several modern Asian populations. The sequences were primarily assigned into each mtDNA haplogroups, and compared with modern populations. Results Fragments of mtDNA HVRⅠ, 364 bp in length, were recovered from 7 individuals from the Zhukaigou archaeological site. 7 sequence types and 15 polymorphism sites were found. Haplogroup distributions of the ancient individuals were investigated according to variations in the HVRⅠ sequence. ConclusionThe matrilineal genetic structure of the Zhukaigou site population is close to that of the later Yinniugou population and modern populations in this area. This aDNA study shows the continuity of the matrilineal genetic structure in the populations of the south central Inner Mongolia.

Key words: DNA, mitochondrial, aDNA, phylogenetic analyses

中图分类号: 

  • Q987
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