关键词: 胸部损伤, 自体血液回输, 血液滤过, 动物, 实验

Abstract: Objective To evaluate the functioin of a new muti-functional device of thoracic cavity closed drainage system with animal experimental study. Methods Twelve dogs were randomly divided into experimental and control groups (n=6). They were treated with two kinds of thoracic cavity closed drainage system respectively after artificial hemopneumothorax. The time of thoracic cavity closed drainage, anti-tensile strength,and hemoglobin contents in peripheral venous blood before operation and after reinfusion were observed. Results The time of thoracic cavity closed drainage in experimental group was (44.67±8.89)s and that in control group was (451.67±63.56)s, there was significantly difference (P<0.000 1). The anti-tensile strength of two devices in two groups were （55.17±0.71）N and （35.48±0.57）N (P<0.05)， respectively. The hemoglobin in experimental group was (106.33±9.56) g•L^-1 averagely after autotransfusion and that in control group was (63.83±7.19)g•L^-1 after transfusion with saline, there was significantly difference (P<0.001). All animals were survived in experimental group, whereas 3 animals were survived in control group in a period of 24 hours. Conclusion The new device is more availability and convenient than existing system. The new one has autotransfusion function specially.

Key words: chest injury, autotransfusion, hemofiltration, animals, laboratory