[1] Kanasaki K, Nagai T, Nitta K, et al. N-acetyl-seryl-aspartyl-lysyl-proline:a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes[J]. Front Pharmacol, 2014, 5:70-81. [2] Hrenak J, Paulis L, Simko F. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP):Potential target molecule in research of heart, kidney and brain[J]. Curr Pharm Des, 2015, 21(35):5135-5143. [3] Mnguni AT, Engel ME, Borkum MS, et al. The effects of angiotensin converting enzyme inhibitors (ACE-I) on human N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) levels:a systematic review and Meta-Analysis[J]. PLoS One, 2015, 10(12):e0143338. [4] Mnguni AT, Engel ME, Borkum MS, et al. The Effects of Angiotensin Converting Enzyme Inhibitors (ACE-I) on Human N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) Levels:A Systematic Review and Meta-Analysis[J]. PLoS One, 2015, 10(12):e0143338. [5] 刘晓亚,刘瑞霞,崔立建,等.胆管结扎和四氯化碳诱导Wistar大鼠肝纤维化模型的建立及相关指标的对比分析[J].临床肝胆病杂志,2015,31(2):219-224. [6] Chen YW, Liu BW, Zhang YJ, et al. Preservation of basal AcSDKP attenuates Carbon tetrachloride-induced fibrosis in the rat liver[J]. J Hepatol, 2010, 53(3):528-536. [7] Yuan J, Shen Y, Yang X, et al. Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models[J]. BMC Nephrol, 2017, 18(1):314-324. [8] Zhu L, Cheng M, Liu Y, et al. Thymosin-β4 inhibits proliferation and induces apoptosis of hepatic stellate cells through PI3K/AKT pathway[J]. Oncotarget, 2017, 8(40):68847-68853. [9] Deng H, Xu H, Zhang X, et al. Protective effect of Ac-SDKP on alveolar epithelial cells through inhibition of EMT via TGF-β1/ROCK1 pathway in silicosis in rat[J]. Toxicol Appl Pharmacol, 2016, 294:1-10. [10] Mitrovic V, Seferovic P, Dodic S, et al. Cardio-renal effects of the A1 adenosine receptor antagonist SLV320 in patients with heart failure[J]. Circ Heart Fail, 2009, 2(6):523-531. [11] Stienstra R, Saudale F, Duval C, et al. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity[J]. Hepatology, 2010, 51(2):511-522. [12] Hu Q, Li J, Nitta K, et al. FGFR1 is essential for N-acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p[J]. Biochem Biophys Res Commun, 2018, 495(3):2214-2220. [13] Masuyer G, Douglas RG, Sturrock ED, et al. Structural basis of Ac-SDKP hydrolysis by Angiotensin-Ⅰ converting enzyme[J]. Sci Rep, 2015, 5:13742. [14] Srivastava SP, Shi S, Kanasaki M, et al. Effect of antifibrotic MicroRNAs crosstalk on the action of n-acetyl-seryl-aspartyl-lysyl-proline in diabetes-related kidney fibrosis[J]. Sci Rep, 2016, 6:29884.doi:10.1038/srep 29884. [15] Li J, Shi S, Srivastava SP, et al. FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway[J]. Cell Death Dis, 2017, 8(8):e2965. [16] 闫静波.AcSDKP对硅肺纤维化大鼠胶原含量及NF-κBp65表达的影响[J].重庆医学,2013(26):3139-3141. [17] Conte E, Fagone E, Gili E, et al. Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis[J]. Oncotarget, 2016, 7(23):33841-33854. [18] Liao TD, Nakagawa P, Janic B, et al. N-Acetyl-Seryl-Aspartyl-Lysyl-Proline:mechanisms of renal protection in mouse model of systemic lupus erythematosus[J]. Am J Physiol Renal Physiol, 2015, 308(10):F1146-F1154. [19] Ma X, Yuan Y, Zhang Z, et al. An analog of Ac-SDKP improves heart functions after myocardial infarction by suppressing alternative activation (M2) of macrophages[J]. Int J Cardiol, 2014, 175(2):376-378. [20] Monge M, Paquet V, Bergerot D, et al. Dose-effect relationship of perindopril 10, 14 and 20mg assessed by urine and plasma AcSDKP levels in mildly sodium-depleted healthy volunteers[J]. Int J Cardiol, 2016, 222:648-653. [21] 牛学敏,王宝玉,王洋,等.PTEN在CCl_4诱导肝纤维化大鼠模型中的作用及益气活血方对其的影响[J].临床肝胆病杂志,2018,34(1):122-128. [22] Jiang Y, Han T, Zhang ZG, et al. Potential role of thymosin beta 4 in the treatment of nonalcoholic fatty liver disease[J]. Chronic Dis Transl Med, 2017, 3(3):165-168. [23] Hong Y, Yao Q, Zheng L. Thymosin β4 attenuates liver fibrosis via suppressing Notch signaling[J]. Biochem Biophys Res Commun, 2017, 493(4):1396-1401. |