吉林大学学报(医学版) ›› 2019, Vol. 45 ›› Issue (03): 673-677.doi: 10.13481/j.1671-587x.20190334

• 临床医学 • 上一篇    

胃癌术后胃瘫综合征患者相关危险因素及其临床治疗

张昊龙, 于镇滔, 高子涵, 吴元玉, 房学东   

  1. 吉林大学中日联谊医院胃肠结直肠肛门外科, 吉林 长春 130033
  • 收稿日期:2019-01-22 发布日期:2019-06-05
  • 通讯作者: 房学东,教授,主任医师,博士研究生生导师(Tel:0431-89876798,E-mail:fangxd1961@163.com) E-mail:fangxd1961@163.com
  • 作者简介:张昊龙(1992-),男,吉林省长春市人,在读医学硕士,主要从事胃结直肠肛门外科方面的研究。
  • 基金资助:
    吉林省教育厅科研项目资助课题(吉教科字(2015)39号)

Related risk factors and clinical treatment of patients with PGS after gastric cancer operation

ZHANG Haolong, YU Zhentao, GAO Zihan, WU Yuanyu, FANG Xuedong   

  1. Department of Gastrointestinal Colorectal Anus Surgery, China-Japan Union Hospital, Jilin University, Changchun 130033, China
  • Received:2019-01-22 Published:2019-06-05

摘要: 目的:探讨胃癌患者术后出现术后胃瘫综合征(PGS)的原因,阐明引起胃癌术后PGS的相关危险因素及其治疗措施,为提高PGS患者的生存质量提供参考。方法:回顾性分析1 015例行胃癌根治术患者的临床资料,按术后是否出现PGS将其分为PGS组(n=39)及非PGS组(n=976),将2组患者按年龄、性别、手术方式及吻合形式进行单因素分析,分析发生PGS的影响因素。结果:≥56岁患者中PGS发生率与<56岁患者比较差异无统计学意义(P>0.05),男性患者PGS发生率与女性患者比较差异无统计学意义(P>0.05),行开腹胃癌根治术患者PGS发生率高于行腹腔镜胃癌根治术患者(P<0.01),采用BillrothⅠ式吻合患者PGS发生率低于采用BillrothⅡ式吻合患者(P<0.01)。所有PGS患者经药物和心理等多方面联合系统治疗后均治愈出院。结论:胃癌根治术后PGS的发生与患者性别和年龄等生理性因素无关。腹腔镜胃癌根治术后PGS发生率低于开腹胃癌根治术,经BillrothⅠ式吻合后出现PGS的概率低于BillrothⅡ式。

关键词: 胃肿瘤, 术后胃瘫综合征, 危险因素, 胃癌根治术

Abstract: Objective:To investigate the reasons for the occurrence of postsurgical gastroparesis syndrome (PGS) in the patients with gastric cancer after gastric cancer operation, and to elucidate the related risk factors and treatment measures for the PGS patients,and to provide the basis for improving the quality of life of the patients with PGS. Methods:The clinical data of 1 015 patients underwent radical gastrectomy were retrospectively analyzed and the patients were divided into PGS group(n=39) and non-PGS group(n=976) according to whether the PGS appeared after operation. Single factor analysis was performed according to age, gender, surgical method and anastomosis in the patients in two groups.The risk factors related to PGS were analyzed. Results:There was no difference in the incidence of PGS in the patients ≥ 56 years old and the patients <56 years old (P>0.05); the incidence of PGS in the male patients was not significantly different from that in the female patients(P>0.05); the incidence of PGS in the patients underwemt radical gastrectomy was higher than that in the patients underwent laparoscopic radical gastrectomy (P<0.01); the incidence of PGS in the patients underwent Billroth Ⅰ anastomosis was lower than that in the patients underwent Billroth Ⅱ anastomosis (P<0.01). All the PGS patients were cured after treated with a combination method of drugs and psychology. Conclusion:The occurrence of PGS after radical gastrectomy has nothing to do with the physiological factors of the patients such as gender and age. The incidence of PGS after laparoscopic radical gastrectomy is lower than that after open radical gastrectomy,and the incidence of PGS after Billroth Ⅰ anastomosis is lower than that after Billroth Ⅱ anastomosis.

Key words: stomach neoplasms, postsurgical gastroparesis syndrome, risk factors, treatment, radical gastrecyomy, laparoscope

中图分类号: 

  • R735.2