[1] Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012[J]. CA Cancer J Clin, 2015, 65(2):87-108. [2] 陈万青, 郑荣寿, 张思维, 等. 2013年中国恶性肿瘤发病和死亡分析[J]. 中国肿瘤, 2017(1):1-7. [3] Jiang J, Cao D, Jia Z, et al. The green tea polyphenol epigallocatechin-3-gallate effectively inhibits helicobacter pylori-induced gastritis in Mongolian gerbils[J]. Int J Clin Exp Med, 2016, 9(2):2479-2485. [4] Oshima H, Oshima M, Inaba K, et al. Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice[J]. EMBO J, 2004, 23(7):1669-1678. [5] 尤丽丽, 曹东慧, 姜晶, 等. 原发胃癌转基因小鼠模型的病理特征及应用新进展[J]. 世界华人消化杂志, 2015, 23(17):2754-2760. [6] Oshima H, Matsunaga A, Fujimura T, et al. Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway[J]. Gastroenterology, 2006, 131(4):1086-1095. [7] Echizen K, Hirose O, Maeda Y, et al. Inflammation in gastric cancer:Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways[J]. Cancer Sci, 2016, 107(4):391-397. [8] Cao D, Jiang J, Tsukamoto T, et al. Canolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic mice[J].PLoS One, 2015, 10(3):e0120938. [9] Cao D, Jiang J, You L, et al. The protective effects of 18β-glycyrrhetinic acid on Helicobacter pylori-infected gastric mucosa in Mongolian gerbils[J]. Biomed Res Int, 2016, 2016(5):494373. [10] 尤丽丽, 曹东慧, 姜晶, 等. 18β-甘草次酸对K19-C2mE转基因鼠胃肿瘤的抑制作用及其机制[J]. 吉林大学学报:医学版, 2016,42(2):221-225. [11] Wu X, Zhang L, Gurley E, et al. Prevention of free fatty acid-induced hepatic lipotoxicity by 18 beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways[J]. Hepatology, 2008, 47(6):1905-1915. [12] Hasan SK, Siddiqi A, Nafees S, et al. Chemopreventive effect of 18β-glycyrrhetinic acid via modulation of inflammatory markers and induction of apoptosis in human hepatoma cell line (HepG2)[J]. Mol Cell Biochem, 2016, 416(1-2):169-177. [13] Parida PK, Sau A, Ghosh T, et al. Synthesis and evaluation of triazole linked glycosylated 18β-glycyrrhetinic acid derivatives as anticancer agents[J]. Bioorg Med Chem Lett, 2014, 24(16):3865-3868. [14] Gao C, Dai FJ, Cui HW, et al. Synthesis of novel heterocyclic ring-fused 18β-glycyrrhetinic acid derivatives with antitumor and antimetastatic activity[J]. Chem Biol Drug Des, 2014, 84(2):223-233. [15] 王银环,范钰,张尤历,等. 18β-甘草次酸对人胃癌细胞BGC823增殖的抑制[J]. 江苏大学学报:医学版, 2007, 17(3):251-253. [16] 贾洪岩,林芳,王立敏,等. 甘草次酸对人胃癌HGC-27的抑制增殖和诱导凋亡作用[J]. 黑龙江医药科学, 2016, 39(2):88-92. [17] 李凤斐, 杜维桓, 杨桂彬,等. ATP4B在不同程度胃黏膜病变中的表达及其与幽门螺杆菌感染的关系[J]. 北京医学, 2014, 36(1):12-14. [18] Judd LM, Andringa A, Rubio CA, et al. Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors[J]. J Gastroenterol Hepatol, 2005, 20(8):1266-1278. [19] Rojo JV, Merino AM, González LO, et al. Expression and clinical significance of pepsinogen C in epithelial ovarian carcinomas[J]. Eur J Obstet Gynecol Reprod Biol, 104(1):58-63. [20] Fernández R, Vizoso F, Rodríguez JC, et al. Expression and prognostic significance of pepsinogen C in gastric carcinoma[J]. Ann Surg Oncol, 2000, 7(7):508-514. [21] Li G, Su Q, Liu H, et al. Frizzled7 promotes epithelial-to-mesenchymal transition and stemness via activating canonical Wnt/β-catenin pathway in gastric cancer[J]. Int J Biol Sci, 2018, 14(3):280-293. [22] Xu H, Posner GH, Stevenson M, et al. Apc MIN modulation of vitamin D secosteroid growth control[J]. Carcinogenesis, 2010, 31(8):1434-1441. [23] Molaei F, Forghanifard MM, Fahim Y, et al. Molecular signaling in tumorigenesis of gastric cancer[J]. Iran Biomed J, 2018, 22(4):217-230. [24] 和水祥,张丹,禄韶英.胃癌的分子机制及靶向诊断研究进展[J].西安交通大学学报:医学版,2016,37(4):461-472. [25] 师阿盟,史海涛,董蕾,等.SDF-1/CXCR7对胃癌SGC-7901细胞合成及分泌炎症因子的影响[J].西安交通大学学报:医学版,2017,38(1):34-38,43. |