Journal of Jilin University(Medicine Edition) ›› 2023, Vol. 49 ›› Issue (4): 1083-1091.doi: 10.13481/j.1671-587X.20230433
• Review • Previous Articles
Research progress in potential biomarkers of vascular mild cognitive impairment
-
Received:2022-04-12Online:2023-07-28Published:2023-07-26
CLC Number:
- R743
Cite this article
share this article
| 1 | 田金洲， 解恒革， 秦 斌， 等. 中国血管性轻度认知损害诊断指南［J］. 中华内科杂志， 2016， 55（3）： 249-256. |
| 2 | 周凯歌. 血管性认知障碍患者认知功能、神经影像学及代谢组学相关研究［D］. 上海： 第二军医大学，2014. |
| 3 | GHAFAR M Z A A， MIPTAH H N， O’CAOIMH R. Cognitive screening instruments to identify vascular cognitive impairment： a systematic review［J］. Int J Geriatr Psychiatry， 2019， 34（8）： 1114-1127. |
| 4 | SMITH E E， SCHNEIDER J A， WARDLAW J M，et al.Cerebral microinfarcts： the invisible lesions［J］. Lancet Neurol， 2012， 11（3）： 272-282. |
| 5 | 韩晓蕾， 王晓杰， 杜怡峰. 脑小血管病与认知障碍［J］. 中国实用内科杂志， 2021， 41（7）： 575-578. |
| 6 | CHARLTON R A， BARRICK T R， MCINTYRE D J， et al. White matter damage on diffusion tensor imaging correlates with age-related cognitive decline［J］. Neurology， 2006， 66（2）： 217-222. |
| 7 | TOZER D J， ZEESTRATEN E， LAWRENCE A J， et al. Texture analysis of T1-weighted and fluid-attenuated inversion recovery images detects abnormalities that correlate with cognitive decline in small vessel disease［J］. Stroke，2018，49（7）：1656-1661. |
| 8 | BETROUNI N， YASMINA M， BOMBOIS S， et al. Texture features of magnetic resonance images： an early marker of post-stroke cognitive impairment［J］. Transl Stroke Res， 2020， 11（4）： 643-652. |
| 9 | DE JONG F J， SCHRIJVERS E M， IKRAM M K，et al.Retinal vascular caliber and risk of dementia： the Rotterdam study［J］. Neurology， 2011， 76（9）： 816-821. |
| 10 | QIU C， COTCH M F， SIGURDSSON S， et al. Cerebral microbleeds， retinopathy， and dementia： the AGES-Reykjavik study［J］. Neurology， 2010， 75（24）： 2221-2228. |
| 11 | YUAN M， BI X. Therapeutic and diagnostic potential of microRNAs in vascular cognitive impairment［J］. J Mol Neurosci， 2020， 70（10）： 1619-1628. |
| 12 | CIPOLLINI V， TROILI F， GIUBILEI F. Emerging biomarkers in vascular cognitive impairment and dementia： from pathophysiological pathways to clinical application［J］. Int J Mol Sci， 2019， 20（11）： 2812. |
| 13 | HUANG S E， ZHAO J P， HUANG D X， et al. Serum miR-132 is a risk marker of post-stroke cognitive impairment［J］. Neurosci Lett， 2016， 615： 102-106. |
| 14 | YANG F W， WANG H， WANG C， et al. Upregulation of acetylcholinesterase caused by downregulation of microRNA-132 is responsible for the development of dementia after ischemic stroke［J］. J Cell Biochem， 2020， 121（1）： 135-141. |
| 15 | PRABHAKAR P， CHANDRA S R， CHRISTOPHER R.Circulating microRNAs as potential biomarkers for the identification of vascular dementia due to cerebral small vessel disease［J］. Age Ageing， 2017， 46（5）： 861-864. |
| 16 | BARBAGALLO C， MOSTILE G， BAGLIERI G，et al. Specific signatures of serum miRNAs as potential biomarkers to discriminate clinically similar neurodegenerative and vascular-related diseases［J］. Cell Mol Neurobiol， 2020， 40（4）： 531-546. |
| 17 | SONNTAG W E， DEAK F， ASHPOLE N， et al. Insulin-like growth factor-1 in CNS and cerebrovascular aging［J］. Front Aging Neurosci， 2013， 5： 27. |
| 18 | GEYTER D D， STOOP W， SARRE S， et al. Neuroprotective efficacy of subcutaneous insulin-like growth factor-Ⅰ administration in normotensive and hypertensive rats with an ischemic stroke［J］. Neuroscience， 2013， 250： 253-262. |
| 19 | DIK M G， PLUIJM S M， JONKER C， et al. Insulin-like growth factor Ⅰ （IGF-Ⅰ） and cognitive decline in older persons［J］.Neurobiol Aging，2003，24（4）：573-581. |
| 20 | CALVO D， GUNSTAD J， MILLER L A， et al. Higher serum insulin-like growth factor-1 is associated with better cognitive performance in persons with mild cognitive impairment［J］. Psychogeriatrics，2013，13（3）： 170-174. |
| 21 | ONG L K， CHOW W Z， TEBAY C， et al. Growth hormone improves cognitive function after experimental stroke［J］. Stroke， 2018， 49（5）： 1257-1266. |
| 22 | TSAI C L， HUANG T H， TSAI M C. Neurocognitive performances of visuospatial attention and the correlations with metabolic and inflammatory biomarkers in adults with obesity［J］. Exp Physiol， 2017， 102（12）： 1683-1699. |
| 23 | ZHANG F， WANG S P， SIGNORE A P， et al. Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia［J］. Stroke， 2007， 38（8）： 2329-2336. |
| 24 | MATOCHIK J A， LONDON E D， YILDIZ B O，et al. Effect of leptin replacement on brain structure in genetically leptin-deficient adults［J］. J Clin Endocrinol Metab， 2005， 90（5）： 2851-2854. |
| 25 | PANNACCIULLI N， LE D S， CHEN K W， et al. Relationships between plasma leptin concentrations and human brain structure： a voxel-based morphometric study［J］. Neurosci Lett， 2007， 412（3）： 248-253. |
| 26 | OOMURA Y， HORI N， SHIRAISHI T， et al. Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK Ⅱ phosphorylation in rats［J］. Peptides， 2006， 27（11）： 2738-2749. |
| 27 | FANTUZZI G， FAGGIONI R. Leptin in the regulation of immunity， inflammation， and hematopoiesis［J］. J Leukoc Biol， 2000， 68（4）： 437-446. |
| 28 | TANG C H， LU D Y， YANG R S， et al. Leptin-induced IL-6 production is mediated by leptin receptor， insulin receptor substrate-1，phosphatidylinositol 3- kinase， Akt， NF-kappaB， and p300 pathway in microglia［J］. J Immunol， 2007， 179（2）： 1292-1302. |
| 29 | DU Y， SONG Y F， ZHANG X J， et al. Leptin receptor deficiency protects mice against chronic cerebral hypoperfusion-induced neuroinflammation and white matter lesions［J］. Mediators Inflamm， 2020， 2020： 7974537. |
| 30 | LI X L， AOU S， OOMURA Y， et al. Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents［J］. Neuroscience， 2002， 113（3）： 607-615. |
| 31 | ZEKI AL HAZZOURI A， STONE K L， HAAN M N， et al. Leptin， mild cognitive impairment， and dementia among elderly women［J］. J Gerontol A Biol Sci Med Sci， 2013， 68（2）： 175-180. |
| 32 | BEDNARSKA-MAKARUK M， GRABAN A， WIŚNIEWSKA A， et al. Association of adiponectin， leptin and resistin with inflammatory markers and obesity in dementia［J］. Biogerontology， 2017， 18（4）： 561-580. |
| 33 | 赵建华， 田小军， 刘艳霞， 等. 非痴呆型血管性认知功能障碍患者血清瘦素水平与执行功能的关系［J］. 中国老年学杂志， 2012， 32（15）3156-3158 |
| 34 | 邓玉燕. 血清瘦素与脑梗死后认知障碍的研究［D］. 长春： 吉林大学，2019. |
| 35 | LIU M， ZHOU K G， LI H L， et al. Potential of serum metabolites for diagnosing post-stroke cognitive impairment［J］. Mol Biosyst， 2015， 11（12）： 3287-3296. |
| 36 | COGO A， MANGIN G， MAÏER B， et al. Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline［J］. Mol Neurodegener， 2021， 16（1）： 7. |
| 37 | 陈 爽. 血浆代谢物与血管性认知功能障碍的相关性研究［D］. 大连： 大连医科大学，2020. |
| 38 | LIU Y， CHAN D K Y， THALAMUTHU A， et al. Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia［J］. Comput Struct Biotechnol J， 2020， 18： 1613-1624. |
| 39 | 黄晓芸， 刘 军， 黄凯帆， 等. 血管性认知障碍患者血清脂蛋白相关磷脂酶A2水平变化及其对认知障碍的预测价值［J］. 新乡医学院学报， 2021， 38（1）： 31-35，40. |
| 40 | OGBONNAYA E S， CLARKE G， SHANAHAN F， et al. Adult hippocampal neurogenesis is regulated by the microbiome［J］. Biol Psychiatry， 2015， 78（4）： e7-e9. |
| 41 | CHEN R Z， XU Y， WU P， et al. Transplantation of fecal microbiota rich in short chain fatty acids and butyric acid treat cerebral ischemic stroke by regulating gut microbiota［J］. Pharmacol Res， 2019， 148： 104403. |
| 42 | LING Y， GONG T Y， ZHANG J M， et al. Gut microbiome signatures are biomarkers for cognitive impairment in patients with ischemic stroke［J］. Front Aging Neurosci， 2020， 12： 511562. |
| 43 | MATTSSON N， ANDREASSON U， ZETTERBERG H， et al. Association of plasma neurofilament light with neurodegeneration in patients with alzheimer disease［J］. JAMA Neurol， 2017，74（5）： 557-566. |
| 44 | DUERING M， KONIECZNY M J， TIEDT S， et al. Serum neurofilament light chain levels are related to small vessel disease burden［J］. J Stroke， 2018， 20（2）： 228-238. |
| 45 | PETERS N， VAN LEIJSEN E， TULADHAR A M， et al. Serum neurofilament light chain is associated with incident lacunes in progressive cerebral small vessel disease［J］. J Stroke， 2020， 22（3）： 369-376. |
| 46 | MA W B， ZHANG J J， XU J L， et al. Elevated levels of serum neurofilament light chain associated with cognitive impairment in vascular dementia［J］. Dis Markers， 2020， 2020： 6612871. |
| 47 | HOYER-KIMURA C， KONHILAS J P， MANSOUR H M， et al. Neurofilament light： a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia［J］. J Neuroinflammation， 2021， 18（1）： 236. |
| 48 | PAN P， MA Z N， ZHANG Z， et al. Acupuncture can regulate the peripheral immune cell spectrum and inflammatory environment of the vascular dementia rat， and improve the cognitive dysfunction of the rats［J］. Front Aging Neurosci， 2021， 13： 706834. |
| 49 | ZHI H， WANG Y， CHANG S C， et al. Acupuncture can regulate the distribution of lymphocyte subsets and the levels of inflammatory cytokines in patients with mild to moderate vascular dementia［J］. Front Aging Neurosci， 2021， 13： 747673. |
| 50 | HILAL S， IKRAM M A， VERBEEK M M， et al. C-reactive protein， plasma amyloid-β levels， and their interaction with magnetic resonance imaging markers［J］. Stroke， 2018， 49（11）： 2692-2698. |
| 51 | RAVAGLIA G， FORTI P， MAIOLI F， et al. Blood inflammatory markers and risk of dementia： the Conselice Study of Brain Aging［J］. Neurobiol Aging， 2007， 28（12）： 1810-1820. |
| 52 | SINGH-MANOUX A， DUGRAVOT A， BRUNNER E，et al. Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife［J］. Neurology， 2014， 83（6）： 486-493. |
| 53 | BJERKE M， JONSSON M， NORDLUND A， et al. Cerebrovascular biomarker profile is related to white matter disease and ventricular dilation in a LADIS substudy［J］.Dement Geriatr Cogn Dis Extra， 2014， 4（3）： 385-394. |
| 54 | CANDELARIO-JALIL E， THOMPSON J， TAHERI S，et al. Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment［J］. Stroke， 2011， 42（5）：1345-1350. |
| 55 | DUITS F H， HERNANDEZ-GUILLAMON M， MONTANER J， et al. Matrix metalloproteinases in Alzheimer’s disease and concurrent cerebral microbleeds［J］.J Alzheimers Dis，2015，48（3）： 711-720. |
| 56 | DERA H A. Neuroprotective effect of resveratrol against late cerebral ischemia reperfusion induced oxidative stress damage involves upregulation of osteopontin and inhibition of interleukin-1beta［J］. J Physiol Pharmacol， 2017， 68（1）： 47-56. |
| 57 | CHAI Y L， CHONG J R， RAQUIB A R， et al. Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment［J］. Sci Rep，2021，11（1）： 4010. |
| 58 | 雷佳慧， 谢 晶， 顾文博， 等.纤维蛋白原及D-二聚体在哮喘-慢性阻塞性肺疾病重叠患者的临床研究［J］.中国实用内科杂志，2021，41（3）： 219-223. |
| 59 | VAN OIJEN M， WITTEMAN J C， HOFMAN A，et al.Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia［J］. Stroke， 2005， 36（12）： 2637-2641. |
| 60 | STOTT D J， SPILG E， CAMPBELL A M， et al. Haemostasis in ischaemic stroke and vascular dementia［J］. Blood Coagul Fibrinolysis，2001，12（8）： 651-657. |
| 61 | SCHNEIDER J A， WILSON R S， BIENIAS J L，et al. Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology［J］. Neurology，2004， 62（7）： 1148-1155. |
| 62 | CARCAILLON L， GAUSSEM P， DUCIMETIÈRE P， et al. Elevated plasma fibrin D-dimer as a risk factor for vascular dementia： the Three-City cohort study［J］. J Thromb Haemost， 2009， 7（12）： 1972-1978. |
| [1] | Yunke LUO,Jian ZHANG,Wenwen ZHANG,Zongsheng DUAN,Hushan WANG,Yiheng WANG. Intracranial aneurysm rupture complicated with acute myocardial infarction: A case report and literature review [J]. Journal of Jilin University(Medicine Edition), 2023, 49(3): 777-781. |
| [2] | Jun ZHU,Nan ZHOU,Deming LI. Improvement effect of propofol postconditioning on focal cerebral ischemia-reperfusion injury in rats and its mechanism [J]. Journal of Jilin University(Medicine Edition), 2023, 49(1): 46-54. |
| [3] | . [J]. Journal of Jilin University(Medicine Edition), 2022, 48(6): 1635-1643. |
| [4] | Zehua GONG,Junjie LIU,Jiwei XU,Jianmin LI. Effects of ceftriaxone on activation of astrocytes and inflammation reaction in rats with subarachnoid hemorrhage [J]. Journal of Jilin University(Medicine Edition), 2021, 47(6): 1462-1468. |
| [5] | Jiayi LI,Xiaojing JIA,Shaojie JIA,Yan MA,Yuxiu SHEN,Xin LIU,Hongyan QU,Ge BAI,Na CHENG. Effect of dual anti-platelet therapy with aspirin and clopidogrel on bleeding regression and prognosis of acute ischemic stroke patients complicated with cerebral microbleeds [J]. Journal of Jilin University(Medicine Edition), 2021, 47(6): 1531-1537. |
| [6] | Haoyang DUAN,Zhenlan LI,Fuxian LYU,Na LIU,Zhaohong YAN. Effect evaluation of isokinetic muscle strength training with different flexor and extensor muscle strength ratios in treatment of hyperextension of knee after stroke [J]. Journal of Jilin University(Medicine Edition), 2021, 47(6): 1538-1543. |
| [7] | Rubin HAO,Haotian WANG,Lihua YANG,Chun MA,Shuling Li,Xinxin LI,Tieshu LI. Neuroprotective effect of nasal inhalation of miRNA-124 nanoparticles on ischemic stroke model rats [J]. Journal of Jilin University(Medicine Edition), 2020, 46(6): 1208-1214. |
| [8] | BU Yi, ZHANG Shuo, QIAN Xudong, WANG Hongmei, DOU Zhijie. Expression of insulin-like growth factor binding protein-3 in ischemic brain tissue of cerebral infarction model rats and its relationship with angiogenesis [J]. Journal of Jilin University(Medicine Edition), 2020, 46(04): 759-764. |
| [9] | BU Yi, ZHANG Shuo, QIAN Xudong, WANG Hongmei, DOU Zhijie. Expressions of Galectin-3 and MMP-9 in brain tissue of mice with acute cerebral infarction and intervention effect of nimodipine [J]. Journal of Jilin University(Medicine Edition), 2020, 46(03): 551-556. |
| [10] | JIAO Guangmei, SHAN Hailei, ZHANG Xiaoxuan, ZHAO Liang, DOU Zhijie, KANG Lingling, MA Zheng, SUN Yanjun, YANG Ning. Protective effect of Shuxuening Injection on brain tissue of rats with acute cerebral infarction and its mechanism [J]. Journal of Jilin University(Medicine Edition), 2020, 46(03): 557-562. |
| [11] | BI Yongzhi, MA Fen, SHI Junxia, SONG Linlin, LI Linze. Protective effect of emodin on focal cerebral ischemia in rats and its mechanism [J]. Journal of Jilin University(Medicine Edition), 2020, 46(03): 569-574. |
| [12] | PAN Feng, GUO Xiaqing, SHEN Jiangyi, SU Zhiqiang. Neuroprotective effect of emodin on ischemic stroke model rats and its effect on ERK1/2 signaling pathway [J]. Journal of Jilin University(Medicine Edition), 2019, 45(06): 1212-1217. |
| [13] | LIU Junjie, DU Juan, YANG Yaju, WANG Xue, SUN Yuting, LIU Yao, ZHAO Yaning, LI Jianmin. Protective effect of ceftriaxone on hippocampal neurons in subarachnoid hemorrhage rats and its mechanism [J]. Journal of Jilin University(Medicine Edition), 2019, 45(05): 1069-1074. |
| [14] | LIU Heng, SUN Fan, XU Qianqian, GAO Yanjun, MA Zheng, DOU Zhijie. Effects of baicalin on cognitive function and expression levels of vascular endothelial growth factor and endostatin in cerebral small vessel disease model rats [J]. Journal of Jilin University(Medicine Edition), 2019, 45(05): 1080-1085. |
| [15] | ZHANG Xiaoxuan, ZHU Jiang, LI Jiajia, JIAO Guangmei, SHAN Hailei, ZHAO Liang, DOU Zhijie. Protective effect of butylphthalide on brain in rats with acute ischemic stroke and its mechanism [J]. Journal of Jilin University(Medicine Edition), 2019, 45(04): 843-848. |
|
||