Abstract:

Objective To analyze the clinical data of one patient with inguinal seminoma and testicular seminoma，and to provide the references for the diagnosis and treatment of such patients. Methods The clinical data， imaging features， pathological manifestations， diagnosis， and treatment methods of one patient with primary inguinal seminoma were collected and the relevant literatures were reviewed. Results The patient， a 43-year-old male， was admitted to hospital due to the incidental discovery of a left inguinal mass. The specialized examination results showed a mass with relatively clear boundary， rough surface， palpable nodules， local fluctuation， limited mobility and no epidermal ulceration. The skin temperature was slightly elevated. The morphology and size of both testes were normal with no tenderness. The auxiliary examination results showed that alpha-fetoprotein （AFP） level was 2.3 mg·L^-1， beta-human chorionic gonadotropin （HCG） <0.1 IU·L^-1， and the lactate dehydrogenase （LDH） level was 254.31 IU·L^-1. The results of liver function， renal function， blood routine， and coagulation routine of the patient were all normal.The results of chest CT， ECG， cardiac ultrasound， liver-gallbladder-spleen-pancreas ultrasound， and retroperitoneal ultrasound showed no abnormalities. The preoperative biopsy pathology from the oncology department suggested seminoma. After comprehensive clinical analysis， it was decided to perform the inguinal mass excision and inguinal lymph node dissection. The postoperative pathology was consistent with the preoperative findings， confirming that seminoma with inguinal lymph node metastasis. The follow-up results at 1， 3， 6， and 8 months after operation showed the patient recovered well， and there were no discomfort and capable of light physical activities. The condition remained stable without progression， and the patient had undergone three sessions of radiochemotherapy in the Oncology Department. Conclusion Primary inguinal seminoma has a high cure rate， generally low malignancy， sensitivity to radiotherapy and chemotherapy， and relatively good prognosis.

Key words: Inguinal mass, Primary seminoma, Alpha-fetoprotein, Chorionic gonadotropin, Lactate dehydrogenase