宫颈癌患者术后旋转调强与固定野调强放疗计划的剂量学比较

doi:10.13481/j.1671-587x.20150435

Abstract

Abstract:

Objective To explore the advantages and disadvantages of the intensity modulated arc therapy(IMAT) plans and intensity modulated radiation therapy(IMRT) plan,and to provide the basis for their clinical application. Methods 19 patients with cervical cancer after operation were selected.The patients were scanned by simulation CT,and the targets and organs at risk were contoured. IMAT plan and IMRT plan were designed respectively in Eclipse 8.6 planning system.The treatment time and differences of the dose distribution in the targets and organs at risk of IMAT and IMRT plans were compared. Results The average design time of IMAT and IMRT plans of the 19 patients was (129±3) and (30±1) min(P=0.000);the average treatment time on Varian IX accelerator was (3.17±0.23) and (6.55±0.17) min(P=0.009).The homogeneity index(HI) of targets were 1.08 ± 0.01 and 1.10 ± 0.01(P=0.175).The conformal index(CI) of targets were 0.88 ± 0.01 and 0.82 ± 0.01(P=0.000).IMRT plan had the smaller doses at rectum,bladder,small intestine and neck of femoral compared with IMAT. Conclusion Compared with IMRT,IMAT plan has the advantages in dose distribution at targets and CI,its HI and doses of organs at risk are almost same with IMRT.Compared with IMRT,the design time of IMRT plan is increased three times,and the treatment time is reduced by half.In clinic,if the planning time is affluent,the IMAT plan is recommended.

Key words: cervical neoplsms, intensity modulated arc therapy, intensity modulated radiation therapy

CLC Number:

R737.33

LIU Xiangyu, WANG Huidong, GUO Mingfang, XIE Yue. Comparison of dosiology between intensity-modulated arc therapy plan and fixed field IMRT plan in patients with cervical cancer after operation[J].Journal of Jilin University Medicine Edition, 2015, 41(04): 850-853.

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Comparison of dosiology between intensity-modulated arc therapy plan and fixed field IMRT plan in patients with cervical cancer after operation

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