图像引导放疗技术在直肠癌患者术前调强放疗中的应用

doi:10.13481/j.1671-587x.20160635

Abstract

Abstract:

Objective: To explore the application of image-guided radiotherapy technology(IGRT) in intensity modulated radiation therapy(IMRT) in the patients with rectal cancer before operation,and to analyze its guiding significance for target region.Methods: A total of 67 patients with rectal cancer(Ⅱ-Ⅲ stages,CT3-4N0M0 or CT1-4N1-2M0) were treated with IMRT before operation. IGRT was used for once a week during the radiotherapy and two sets of image contrast errors in the three-dimensional space were obtained.The systematic (Σ) and random (σ) setup errors were calculated.The MPTV was calculated according to the van Herk formula.Results: A total of 389 CBCT scans were analyzed. The error range in the directions of e x, y, z axis were (0.86--1.13), (1.94--2.11),and (1.87--1.81) cm, respectively. The translation errors of the corrected y axis and z axis were less than those before correction (t=3.541, P=0.001; t=3.275, P=0.000); the rotation errors of the corrected x axis and y axis were less than those before correction (t=1.260, P=0.000; t=2.797, P=0.000). Before correction, the MPTV in the directions of x, y, z axis were 2.00, 3.25, and 2.88 cm, respectively, which were 0.73, 1.74, and 1.50 cm after correction, reduced by 1.27, 1.51, and 1.38 cm, respectively.Conclusion: IGRT could effectivly guarantee the accuracy of IMRT of the patients with rectal cancer by reducing the systematic errors and position errors.

Key words: rectal neoplasms, intensity modulated radiation therapy, image-guided radiation therapy technology

CLC Number:

R735.37

XU Dequan, ZHUO Longquan, ZHANG Yongchang, ZHAO Ling. Application of image-guided radiation therapy technology in patients with rectal cancer treated with intensity modulated radiation therapy technology before operation[J].Journal of Jilin University Medicine Edition, 2016, 42(06): 1226-1229.

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Application of image-guided radiation therapy technology in patients with rectal cancer treated with intensity modulated radiation therapy technology before operation

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