Abstract: Objective:To analyze the curative effect of phacoemulsification and to intraocular lens implantation combined with anterior vitrectomy in the children with congenital cataract, and to investigate its effectiveness and security. Methods:A total of 43 cases(49 eyes) of 3-7 years old congenital cataract children who were admitted to our hospital were selected as the subjects. According to different treatment methods, the children were divided into control group (23 cases with 26 eyes) and treatment group (20 cases with 23 eyes). The children in control group were treated with phacoemulsification and intraocular lens implantation and the children in treatment group were treated with phacoemulsification, intraocular lens implantation and anterior vitrectomy. After operation, the vision of the children in two groups was observed; the intraocular pressure(IOP), anterior chamber depth, posterior capsule turbidity and the complications in operation and after operation of the children in two groups were detected by non-contact tonometer and ultrasonic biological microscope. Results:The children in two groups were followed up for an average of 12 months after surgery,and 49 eyes were follow-up after operation.Compared with control group, the vision of the children in treatment group was improved significantly,and the constituent ratio of the children with corrected visual acuity after opertion ≥ 0.5 was significantly increased(P<0.05);the anterior chamber depths was significantly increased(P<0.05) and the posterior capsular opacity was significantly reduced(P<0.05). There were no significant differences in the incidences of IOP, corneal endothelium edema(CE), anterior chamber flash(ACF), and anterior chamber cellulosic exudation(ACCE) of the children in two groups(P>0.05). Conclusion:Phacoemulsification and intraocular lens implantation combined with anterior vitrectomy in the children with congenital cataract can effectively improve the visual acuity, anterior chamber depth and posterior capsule opacity; it is more helpful for the reconstruction of visual function after operation in the children.

Key words: intraocular lens, anterior vitrectomy, congenital cataract, phacoemulsification