Abstract:

To study the relationships between serum follicle stimulating hormone(FSH),luteinizing hormone (LH),testosterone (T),inhibin B(INHB) and sperm density and the significance of serum reproductive hormones in diagnosis of male infertility.Methods  150 patients with male infertility were selected,including 50 cases of oligospermia,50 cases of severe oligospermia,50 cases of azoospermia,and 50 healthy subjects were used as controls(normal sperm density group).Sperm density was detected by computer assisted sperm analysis(CASA).The serum FSH,LH,T,INHB levels were detected by radioimmunoassay.
Results The serum FSH and LH in oligospermia，severe oligospermia and azoospermia groups were significantly higher than those in normal sperm density group (P<0.01)，however the serum INH-B levels were significantly lower (P<0.01).The serum  FSH and LH levels in azoospermia group were significantly higher than those in oligospermia and severe oligospermia groups (P<0.01),while the serum INH-B level was significantly lower (P<0.01).There were significantly negative correlations between sperm density and the levels of FSH，LH (r=－0.562,P<0.001;r=－0.347,P<0.001). There was significantly positive correlation between sperm density and INHB (r=0.623,P<0.001),the sperm density had no correlation with T（r=0.080,P>0.05）.
Conclusion  There are negative correlations between the levels of FSH, LH and sperm density;and  the level of INHB is positively correlated  to the sperm density.

Key words: male infertility；sperm density；reproductive hormones