Abstract:

Abstract:Objective To evaluate the efficacy and  safety of percutaneous transluminal  angioplasty (PTA) in  treatment of patients with arteriosclerosis obliteration of lower extremity,and to provide clinical evidence to improve the operation  success rate of  arteriosclerosis obliteration of lower extremity.Methods 30 patients with rteriosclerosis obliteration of lower extremity（FontainⅡ-Ⅳ stage） were submitted to PTA,in which 11 patients were FontainⅡ,7 patients were Fontain Ⅲ,12  patients wereFontain Ⅳ. The recanalization of occlusion arteries and the improvement of clinical symptoms before and after  operation were observed. Results 45 lower extrem
ity arteries in 30 patients were performed with  PTA.42 lower extremity arteries were successfully recanalized,the opoeration  success rate was 93.3%.In 42 recanalized lower extremity arteries,10 were performed with  intravascular ultrasound ablation,20 were  performed with  intravascular ultrasound ablation +balloon  angiography,12 were performed with  intravascular ultrasound ablation +ballon angiography+stenting.The  clinical symptoms  were ameliorated in 27 patients,in which 11 were Fontain Ⅱ(11/11),7 were Fontain Ⅲ(7/7),9 were Fontain Ⅳ(9/12),so the clinical effective  rate was 90%.There was no significant difference of short-term clinical effective rate  between Fontain Ⅱ and Fontain Ⅲ patients (P>0.05).The short-term clinical effective rates were  significantly different between Fontain Ⅱ,Ⅲ and  Fontain Ⅳ patients (P<0.05). Conclusion Combined treatment of   a variety of endovascular angioplasty  could improve the operation success rate of arteriosclerosis obliteration of lower extremity.PTA is a feasible and effective technique for curring arteriosclerosis obliteration of lower xtremity.

Key words: arteriosclerosis obliteration of lower extremity, percutaneous transluminal angioplasty;intravascular ultrasound ablation;balloon , angioplasty