血管内超声在冠状动脉支架术后再狭窄患者预后影响因素分析中的应用

doi:10.13481/j.1671-587x.20160422

Abstract

Abstract:

Objective: To collect the imaging data and related materials of the patients with in-stent restenosis (ISR) after coronary artery stent operation with intravascular ultrasound (IVUS), and to analyze the risk factors of ISR,and to propose the reasonable intervention strategies. Methods: Fifty patients with ISR were divided into ISR ≤ 50% drug group (n=14 ) and ISR >50% drug group(n=36),including drug-coated balloon therapy group (n=16) and stent treatment group (n=20); IVUS virtual organization technology was used to compare the plaque area, location, tissue composition, thrombus and other factors of the patients in various groups after treatment; the data changes after 6 months of follow-up were analyzed. Results: The IVUS results showed the plaque areas and plaque loads of the ISR patients treated with intervention were significantly reduced compared with before operation(P < 0.05);the plaque compression degree of the patients in drug-coated balloon therapy group was lower than that in stent treatment group(P < 0.05), but the differences were not found between drug-coated balloon therapy group and stent treatment group in fibrous tissue components and calcified tissue proportion(P > 0.05). Conclusion: The ISR rate is higher in the patients with high degree of fiber components, plaque composition heterogeneity and distribution of diffuse tortuous and calcified lesions. ISR has no significant correlation with the plaque wall thickness and lipid content and plaque instability and necrotic tissue proportion.

Key words: in-stent restenosis, intravascular ultrasound, virtual histology, drug-coated balloon

CLC Number:

R541.4

CUI Yan, SHI Yongfeng, GUO Ziyuan, LIU Bin, WANG Jinpeng, ZHAO Lei, WANG Junnan, PIAO Jinhua. Application of intravascular ultrasound in analysis on influencing factors of prognosis in patients with different coronary artery in-stent restenosis[J].Journal of Jilin University Medicine Edition, 2016, 42(04): 746-752.

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Application of intravascular ultrasound in analysis on influencing factors of prognosis in patients with different coronary artery in-stent restenosis

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